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  • P. W. Young, D. G. R. Buckle, +13 authors Steven A. Smith
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental…
  • 1998
  • A radioiodinated ligand, [125I]SB-236636 [(S)-(-)3-[4-[2-[N-(2-benzoxazolyl)-N-methylamino]ethoxy]3-[125I]i odo phenyl]2-ethoxy propanoic acid], which is specific for the gamma isoform of theContinue Reading
  • P. W. Young, Michael Anthony Cawthorne, +6 authors S A Smith
  • Biology, Medicine
  • Diabetes
  • 1995 (First Publication: 1 September 1995)
  • (+/-)-5-([4-[2-Methyl-2(pyridylamino)ethoxy]phenyl]methyl) 2,4-thiazolidinedione (BRL 49653) is a new potent antidiabetic agent that improves insulin sensitivity in animal models of NIDDM. In C57BL/6Continue Reading
  • Lydia Daniels, Peter J. Coyle, Y B Chiao, Robert H. Glew, Rosalind S. Labow
  • Biology, Medicine
  • The Journal of biological chemistry
  • 1981 (First Publication: 25 December 1981)
  • A cytoplasmic beta-glucosidase has been isolated and purified 9,000-fold to homogeneity from the liver of a case of type 1 Gaucher's disease to a specific activity of 400,000 nmol/h/mg of protein.Continue Reading
  • Rebecca P. Hughey, Peter J. Coyle, Norman P. Curthoys
  • Chemistry, Medicine
  • The Journal of biological chemistry
  • 1979 (First Publication: 25 February 1979)
  • gamma-Glutamyltranspeptidase purified following solubilization with Triton X-100 can associate with single-layered [14C]lecithin vesicles. Enzyme activity and radiolabeled vesicles were shown toContinue Reading