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Non-pharmacological breathlessness interventions in lung cancer have proven beneficial. Breathlessness is also a major symptom in chronic obstructive pulmonary disease (COPD). This study measured the effectiveness of a non-exercise-based four-week cognitive-behavioural breathlessness intervention, delivered in a group setting for elderly patients with(More)
Peter Wills is the founder and Chairman of CRI, one of Australia's leading property and infrastructure companies. He is notable for his contribution to the support of Sir Peter Lawler had a distinguished career in the Australian Public Service spanning over 42 years. He joined the Department of PostWar Reconstruction as an economics graduate in 1944 and(More)
BACKGROUND Mucus retention in the lungs is a prominent feature of bronchiectasis. The stagnant mucus becomes chronically colonised with bacteria, which elicit a host neutrophilic response. This fails to eliminate the bacteria, and the large concentration of host-derived protease may contribute to the airway damage. The sensation of retained mucus is itself(More)
Inhaled mannitol has recently been given fast-track status as an investigational drug to treat the lung manifestations of cystic fibrosis. It seems to work in a similar way to nebulized hypertonic saline, osmotically inducing water flux into the bronchial lumen, thereby increasing the hydration of airway mucus, which can then be cleared more effectively by(More)
OBJECTIVE Water is the main constituent of mucus, and its concentration is likely to be important in all aspects of mucus function, including ciliary clearance. The objective of this study was to investigate the effect of water content and osmolality of the mucus on mucociliary transportability. METHODOLOGY Rheology and ciliary transportability of 10(More)
This paper elucidates a close similarity between self-replication of von Neumann's universal constructors and circular computational processes of universal computers that appear in Turing's original proof of the undecidability of the halting problem. The result indicates a possibility of reinter-preting self-replicating machines as attempting to solve the(More)
INTRODUCTION Pigeon fanciers lung, a form of hypersensitivity pneumonitis, is an unusual but important occupational and recreational cause of severe and debilitating breathlessness. CASE PRESENTATION We report the case of a 61-year-old Caucasian man suffering with severe breathlessness due to pigeon fanciers lung. He had previously raced and bred pigeons(More)
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