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Glutamatergic mechanisms have been investigated in postmortem brain samples from schizophrenics and controls. D-[3H]Aspartate binding to glutamate uptake sites was used as a marker for glutamatergic neurones, and [3H]kainate binding for a subclass of postsynaptic glutamate receptors. There were highly significant increases in the binding of both ligands to(More)
A gray seal (Halichoerus grypus) was trained to touch a target on its left or right by responding to pointing signals. The authors then tested whether the seal would be able to generalize spontaneously to altered signals. It responded correctly to center pointing and head turning, center upper body turning, and off-center pointing but not to head turning(More)
Opiate binding sites in sections of human brain were labelled with [3H]etorphine. Many brain areas contained high levels of [3H]etorphine binding sites although the globus pallidus was an exception. Subtraction autoradiography was performed using selective displacement of [3H]etorphine with opioid agonists to visualise mu-, delta- and kappa-opiate receptor(More)
Several recent studies have tested the hypothesis that song quality in adult birds may reflect early developmental conditions, specifically nutritional stress during the nestling period. Whilst all of these earlier studies found apparent links between early nutritional stress and song quality, their results disagree as to which aspects of song learning or(More)
The cost of vocal behaviour is usually expressed in energetic terms; however, many animals may pay additional costs when predators or potential prey eavesdrop on their vocal communication. The northeastern Pacific is home to two distinct ecotypes of killer whales, Orcinus orca, called residents and transients. Resident killer whales feed on fish, a prey(More)