Peter Harvey

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BACKGROUND In order to prevent cardiovascular events, it is essential to effectively manage overall risk of cardiovascular disease. However, despite guideline recommendations to this effect, current management of the major, modifiable cardiovascular risk factors such as hypertension and dyslipidemia is disconnected and patient adherence to therapy is poor.(More)
OBJECTIVES DISTINCT (reDefining Intervention with Studies Testing Innovative Nifedipine GITS - Candesartan Therapy) aimed to determine the dose-response and tolerability of nifedipine GITS and/or candesartan cilexetil therapy in participants with hypertension. METHODS In this 8-week, multinational, multicentre, randomized, double-blind, placebo-controlled(More)
Distributed Constraint Satisfaction Problems provide a natural mechanism for multiagent coordination and agreement. To date, algorithms for Distributed Constraint Satisfaction Problems have tended to mirror existing non-distributed global-search or local-search algorithms. Unfortunately, existing distributed global-search algorithms derive from classical(More)
Algorithms for Distributed Constraint Satisfaction Problems have tended to mirror existing non-distributed global-search or localsearch algorithms. Unfortunately, existing distributed global-search algorithms derive from classical backtracking search methods and require a total ordering over variables for completeness. Distributed variants of local-search(More)
Algorithms for distributed constraint satisfaction problems have tended to mirror existing non-distributed global-search or local-search algorithms. Unfortunately, existing distributed global-search algorithms derive from classical backtracking search methods and require a total ordering over variables for completeness. Distributed variants of local-search(More)
BACKGROUND Single-pill amlodipine/atorvastatin targets the two most common modifiable cardiovascular risk factors, hypertension and dyslipidaemia. We evaluated the clinical utility of this single pill to help patients across Europe and Canada achieve country-specific targets for blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C). DESIGN(More)