Learn More
The power spectra of the photically activated occipital EEGs of 9 mildly to moderately demented probable Alzheimer disease (AD) patients (according to NINCDS-ADRDA criteria), 9 normal age-matched control and 27 normal subjects of different ages were compared. In normal subjects, photic stimulation with rhythmic flashes ranging between 2 and 20 Hz elicited a(More)
To determine the feasibility and safety of image-guided brachytherapy employing a modified open high-field MR system. This is a follow-up study of a development project enabling technologies for interventional use of 1.0T open MRI. Modifications included coils and in-bore visualization, fluoroscopic sequences and user interfaces. We recruited 104 patients(More)
BACKGROUND AND PURPOSE To evaluate whether local tumor control probability (TCP) in stereotactic body radiotherapy (SBRT) varies between lung metastases of different primary cancer sites and between primary non-small cell lung cancer (NSCLC) and secondary lung tumors. MATERIALS AND METHODS A retrospective multi-institutional (n=22) database of 399(More)
Trichlorethylene (tri) is a solvent widely used in mechanical engineering, where it is employed mainly for cleansing and degreasing. Its main advantages are that it is non-inflammable; is an excellent degreasing agent, and is relatively inexpensive. Although tri was for a long time considered to be only very mildly toxic, there has been, in recent years, a(More)
We have shown that the response to flash stimulation of the occipital electroencephalogram (EEG) in Alzheimer disease (AD) patients is smaller than in normal subjects. To ascertain whether this is a specific feature of AD or a nonspecific effect of dementia, we investigated in AD and multi-infarct dementia (MID) patients the relationship between cognitive(More)
PURPOSE Meningiomas are frequent intracranial or spinal neoplasms, which recur frequently and can show aggressive clinical behaviour. We elucidated the impact of the integrin inhibitor cilengitide on migration, proliferation, and radiosensitization of meningioma cells. EXPERIMENTAL DESIGN We analyzed integrin expression in tissue microarrays of human(More)
BACKGROUND/AIM Targeted radiotherapy of liver malignancies has found to be effective in selected patients. A key limiting factor of these therapies is the relatively low tolerance of the liver parenchyma to radiation. We sought to assess the preventive effects of a combined regimen of pentoxifylline (PTX), ursodeoxycholic acid (UDCA) and low-dose low(More)
OBJECTIVES The current literature on stereotactic body radiotherapy (SBRT) for oligometastatic disease is characterized by small patient cohorts with heterogeneous primary tumors, metastases location and dose regimes. Hence, this study established a multi-institutional database of 700 patients treated with SBRT for pulmonary metastases to identify(More)
PURPOSE Most radiobiological models for prediction of tumor control probability (TCP) do not account for the fact that many events could remain unobserved because of censoring. We therefore evaluated a set of TCP models that take into account this censoring. METHODS AND MATERIALS We applied 2 fundamental Bayesian cure rate models to a sample of 770(More)
BACKGROUND F18-fluorodeoxyglucose positron-emission tomography (FDG-PET) reconstruction algorithms can have substantial influence on quantitative image data used, e.g., for therapy planning or monitoring in oncology. We analyzed radial activity concentration profiles of differently reconstructed FDG-PET images to determine the influence of varying(More)