Claim Your Author Page
Ensure your research is discoverable on Semantic Scholar. Claiming your author page allows you to personalize the information displayed and manage publications.
Publisher Summary In the present time there is a true bull market for apoptosis as it has almost become a household word. Even nonspecialists know that fingers and toes do not simply grow out of the… (More)
Apoptosis in T and B lymphocytes is involved in all fundamental processes in the immune system. It is a mechanism to regulate the course of an immune response and to establish immunological memory as… (More)
CD4+CD25+FoxP3+ regulatory T cells (Treg) suppress T cell function and protect rodents from autoimmune disease. Regulation of Treg during an immune response is of major importance. Enhanced survival… (More)
SummarySignals through the CD95 surface receptor can specifically induce apoptosis. Some tumour cell lines are sensitive to CD95 signals, and insensitive cells can be converted to a sensitive… (More)
The CD95 system is one of the best studied death systems and plays an essential role in the immune system, particularly in deletion of peripheral T-cells and in homeostasis of the liver. Here genetic… (More)
TNFa has previously been used in anticancer therapy. However, the therapeutic application of TNFa was largely limited due to its general toxicity and the fact that it activates the NF-KB-family… (More)