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The authors describe a new approach to decision-making in an operational forensic science organization based on a model, embodying the principles of Bayesian inference, which has been developed through workshops run within the Forensic Science Service for forensic science practitioners. Issues which arise from the idea of pre-assessment of cases are(More)
BACKGROUND Evidence suggests a relation between short sleep duration and obesity. OBJECTIVE We assessed energy balance during periods of short and habitual sleep in normal-weight men and women. DESIGN Fifteen men and 15 women aged 30-49 y with a body mass index (in kg/m(2)) of 22-26, who regularly slept 7-9 h/night, were recruited to participate in this(More)
PURPOSE The objective was to systematically review clinical trial data on the effects of statins on high-density lipoproteins (HDL) and to examine the possibility that this provides cardiovascular benefits in addition to those derived from reductions in low-density lipoproteins (LDL). METHODS The PubMed database was searched for publications describing(More)
BACKGROUND Evidence-based randomized clinical trials have shown significant benefit of statin treatment with regard to cardiovascular disease. In anticipation of the National Cholesterol Education Program Adult Treatment Panel IV guidelines, we wanted to assess the current state of lipid goal attainment in the high-risk secondary prevention population in(More)
Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of conjugated dienoic derivatives of linoleic acid. The major dietary source of CLA for humans is ruminant meats, such as beef and lamb, and dairy products, such as milk and cheese. The major isomer of CLA in natural food is cis-9,trans-11 (c9,t11). The commercial preparations(More)
Knowledge management (KM) has received extensive business press over the last two years, and offers substantial promise for long-tern gains in competitiveness and organizational effectiveness. Due to both hype and interest, the field has expanded greatly, making it difficult to understand what's KM, what's worthwhile, and understanding how it might benefit(More)
BACKGROUND Because of hyperglycemia and hyperinsulinemia, diabetic persons have higher cholesterol synthesis and lower cholesterol absorption rates than do nondiabetic persons. Differences in plant sterol efficacy between diabetic and nondiabetic persons have not been examined. OBJECTIVE The objective was to compare the degree of response of plasma lipid(More)