Peter H. J. van der Voort

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OBJECTIVE Continuous venovenous hemofiltration (CVVH) is applied in critically ill patients with acute renal failure for renal replacement. Heparins used to prevent circuit clotting may cause bleeding. Regional anticoagulation with citrate reduces bleeding, but has metabolic risks. The aim was to compare the safety and efficacy of the two. DESIGN(More)
INTRODUCTION The aim of this study was to investigate whether in-hospital mortality was associated with the administered fraction of oxygen in inspired air (FiO2) and achieved arterial partial pressure of oxygen (PaO2). METHODS This was a retrospective, observational study on data from the first 24 h after admission from 36,307 consecutive patients(More)
OBJECTIVE This study was conducted to develop a set of indicators that measure the quality of care in intensive care units (ICU) in Dutch hospitals and to evaluate the feasibility of the registration of these indicators. METHODS To define potential indicators for measuring quality, 3 steps were made. First, a literature search was carried out to obtain(More)
INTRODUCTION The introduction of orthogonal polarization spectral (OPS) imaging in clinical research has elucidated new perspectives on the role of microcirculatory flow abnormalities in the pathogenesis of sepsis. Essential to the process of understanding and reproducing these abnormalities is the method of quantification of flow scores. METHODS In a(More)
OBJECTIVE The study aimed to identify both the frequency and the determinants of drug administration errors in the intensive care unit. DESIGN Administration errors were detected by using the disguised-observation technique (observation of medication administrations by nurses, without revealing the aim of this observation to the nurses). SETTING Two(More)
RATIONALE Delirium is often unrecognized in ICU patients and associated with poor outcome. Screening for ICU delirium is recommended by several medical organizations to improve early diagnosis and treatment. The Confusion Assessment Method for the ICU (CAM-ICU) has high sensitivity and specificity for delirium when administered by research nurses. However,(More)
OBJECTIVE To study whether lactulose or polyethylene glycol is effective to promote defecation in critically ill patients, whether either of the two is superior, and whether the use of enteral laxatives is related to clinical outcome. DESIGN Double-blind, placebo-controlled, randomized study. SETTING Two tertiary intensive care units. PATIENTS Three(More)
BACKGROUND The objective of this study was to elucidate the most practical and effective laboratory measurement for monitoring citrate in critically ill patients undergoing citrate-anticoagulated continuous venovenous haemofiltration (CVVH). METHODS This observational study was performed at the mixed medical and surgical intensive care unit of a regional(More)
BACKGROUND Hyperglycemia and hypoglycemia are associated with adverse clinical outcomes in intensive care patients. In product development studies at 4 ICUs, the safety and performance of an intravascular continuous glucose monitoring (IV-CGM) system was evaluated in 70 postsurgical patients. METHODS The GluCath System (GluMetrics, Inc) used a quenched(More)
INTRODUCTION Prone position is effective in mechanically ventilated patients to improve oxygenation. It is unknown if prone position affects gastric emptying and the ability of continued enteral feeding. AIM To determine tolerance of enteral feeding by measuring gastric residual volumes in enterally fed patients during supine and prone positions. (More)