Peter Galbraith

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A microcytotoxicity assay employing a tetrazolium salt has been adapted for testing the response of human leukemic blast cells to a variety of chemotherapeutic agents. After exposure to various concentrations of drugs, the viability of fresh leukemic blast cells was measured using a tetrazolium salt, MTT, which is converted to blue formazan crystals by(More)
In 1997, the University of New Mexico Health Sciences Center ("the Center") created a managed care plan ("the Plan") for its uninsured patients who were county residents. The Plan's features include pooling the resources of existing county safety-net providers, enrolling patients with primary care providers at easily accessible neighborhood-based clinics,(More)
Human bone marrow contains cells which form leukocyte colonies in semisolid culture media. Each leukocyte colony arises from a single colony-forming cell which is thought to be a unipotential stem cell, and which is subject to regulation in vitro by colony-stimulating factor. In acute myelogenous leukemia variable abnormalities in colony formation by marrow(More)
Cell-cell interaction in vitro was studied by separating normal human bone marrow cells into fractions on the basis of their buoyant density in a linear gradient of bovine serum albumin and by assaying the colonyforming ability of marrow fractions and combinations of marrow fractions in methylcellulose medium without an added extrinsic source of(More)
Granulocyte kinetic studies, using radioactive diisopropylfluorophosphate (DF32P), were performed in 15 patients with acute myelogenous leukemia (AML) and 10 patients with the myelomonoeytic variety (AMML). Attention was focused upon the more differentiated cells present in the blood of the leukemic patients. The patterns of disappearance of in vitro(More)