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  • Nicole Lamanna, Matt E. Kalaycio, +9 authors Mark Anthony Weiss
  • Medicine
  • Journal of clinical oncology : official journal…
  • 1 April 2006
  • PURPOSE Purine analogs and alkylators are important agents for treating chronic lymphocytic leukemia (CLL). Early studies combining fludarabine and chlorambucil were abandoned owing to increasedContinue Reading
  • Linda T. Vahdat, Peter G. Maslak, +4 authors Raymond P. Warrell
  • Medicine
  • Blood
  • 1 December 1994
  • All-trans retinoic acid (RA) has proven a major advance in the treatment of acute promyelocytic leukemia (APL). However, the proper management of patients who present with or develop leukocytosisContinue Reading
  • Virginia M. Klimek, Sophia Fircanis, +7 authors Stephen D. Nimer
  • Biology, Medicine
  • Clinical cancer research : an official journal of…
  • 1 February 2008
  • PURPOSE Epigenetic modulation of gene expression plays an important role in cancer, including leukemia. Furthermore, histone deacetylase inhibitors may induce the reexpression or repression of genesContinue Reading