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  • Emilia Falcetti, Susan M. Hall, +4 authors Lucie H Clapp
  • Medicine
  • American journal of respiratory and critical care…
  • 2010 (First Publication: 1 November 2010)
  • RATIONALE Prostacyclin analogs, used to treat idiopathic pulmonary arterial hypertension (IPAH), are assumed to work through prostacyclin (IP) receptors linked to cyclic AMP (cAMP) generation,Continue Reading
  • Nicholas W Morrell, M. A. Higham, Peter G Phillips, B Haleema Shakur, Paul J. Robinson, Ray J Beddoes
  • Medicine
  • Respiratory research
  • 2005 (First Publication: 1 December 2005)
  • BackgroundMorbidity in COPD results from a combination of factors including hypoxia-induced pulmonary hypertension, in part due to pulmonary vascular remodelling. Animal studies suggest a role ofContinue Reading
  • Jeffrey R. Stokes, Francisco Alamo Romero, +4 authors Thomas B Casale
  • Medicine
  • The Journal of allergy and clinical immunology
  • 2012 (First Publication: 1 February 2012)
  • BACKGROUND Nasal H(3) receptors might have a role in mediating the effects of histamine in patients with allergic rhinitis. OBJECTIVE This study explored the effect of the potent oral H(3) receptorContinue Reading