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The concentrations of hormones measured in serum from maternal blood change dramatically during pregnancy. While the relative contributions of sex steroids shift from maternal ovaries and adrenals to the fetoplacental unit, other maternal tissues such as pituitary and liver respond to increasing concentrations of estrogen and secrete increasing amounts of(More)
In vitro studies with liver homogenates of brook charr (Salvelinus fontinalis) demonstrate that the conversion of thyroxine (T4) to triiodothyronine (T3) is dependent upon temperature, pH, substrate, and homogenate concentration, supporting the hypothesis of an enzymatic hepatic T4 to T3 conversion. Dithiothreitol has a marked stimulatory effect on the rate(More)
BACKGROUND Children with cerebral palsy (CP) are at risk of hip subluxation. Over time, subluxation can lead to dislocation, deformity and pain. Hip surveillance in the form of an X-ray and clinical examination of this 'at risk group' can identify early subluxation. Early subluxation can be treated, preventing hip dislocation in many cases. Hip surveillance(More)
INTRODUCTION The aim of this study was to compare two methods of conservative management of calf spasticity and equinus gait--intramuscular injection of botulinum toxin type A (BTX-A) and serial casting. An economic evaluation framework was adopted to assess whether BTX-A offers value for money in the management of equinus gait due to calf spasticity in(More)
AIM To describe recurrence risk information currently being obtained by families affected by Autism Spectrum Disorder (ASD). METHODS Structured telephone interview of parents of 21 children who received a diagnosis of ASD at Calvary Health Care Tasmania, Hobart, Australia between May 2005 and May 2006. RESULTS Only one of the 21 parents knew their true(More)
Thein vitro hepatic monodeiodination of L-thyroxine (T4) to triiodo-L-thyronine (T3) in rainbow trout (Salmo gairdneri) was found to be pH- and temperature-dependent, and was related to the amount of homogenate in the reaction vessel, suggestive of an enzyme-regulated event. Dithiothreitol (DTT) introduced into the reaction medium stimulated T3 production(More)
A retrospective analysis was conducted of 397 children, ranging in age from 2 to 19 years, attending the Regency Park Centre for Young Disabled in Adelaide. The disorders represented included cerebral palsy, head injury, spina bifida, severe speech and/or language disorders, muscular dystrophy and a number of less common conditions. The incidence of(More)