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User interactions over social networks has been an emergent theme over the last several years. In contrast to previous work we focus on characterizing user communications patterns around an initial post, or conversation root. Specifically, we focus on how other users respond to these roots and how the complete conversation initiated by this root evolves(More)
The accretion of matter onto a massive black hole is believed to feed the relativistic plasma jets found in many active galactic nuclei (AGN). Although some AGN accelerate particles to energies exceeding 10(12) electron volts and are bright sources of very-high-energy (VHE) gamma-ray emission, it is not yet known where the VHE emission originates. Here we(More)
VERITAS, the Very Energetic Radiation Imaging Telescope Array System, is an array of four 12 m diameter imaging atmospheric Cherenkov telescopes for gamma-ray astronomy above 100 GeV currently in operation in Arizona. The VERITAS Collaboration has developed VEGAS, the VERITAS Gamma-ray Analysis Suite, a data-analysis software package for the processing of(More)
The intermediate-frequency peaked BL Lacertae (IBL) object 3C 66A is detected during 2007–2008 in VHE (very high energy; E > 100 GeV) γ rays with the VERITAS stereoscopic array of imaging atmospheric Cherenkov telescopes. An excess of 1791 events is detected, corresponding to a significance of 21.2 standard deviations (σ ), in these observations (32.8 hr(More)
The synthesis and preliminary evaluation of a doxorubicin-formaldehyde conjugate tethered to the nonsteroidal antiandrogen, cyanonilutamide (RU 56279), for the treatment of prostate cancer are reported. The relative ability of the targeting group to bind to the human androgen receptor was studied as a function of tether. The tether served to attach the(More)
VERITAS (the Very Energetic Radiation Imaging Telescope Array System) is the next generation ground-based gamma-ray observatory that is being built in southern Arizona by a collaboration of ten institutions in Canada, Ireland, the U.K. and the U.S.A. VERITAS is designed to operate in the range from 50 GeV to 50 TeV with optimal sensitivity near 200 GeV; it(More)
This study was conducted to evaluate the toxicity and efficacy of Epidoxoform, a prodrug of the active metabolite of epidoxorubicin, in a mouse model of mammary carcinoma. A dose escalation trial established a maximal tolerated dose of 20 mg/kg given intraperitoneally (i.p.) to 6-8 week old female C3 HeJ mice. Two days following injection of 10(6) Gollin-B(More)
Parallel and distributed computing is becoming essential to process in real time the increasingly massive volume of data collected by telecommunications companies. Existing computational paradigms such as MapReduce (and its popular open-source implementation Hadoop) provide a scalable, fault tolerant mechanism for large scale batch computations. However,(More)
While data are growing at a speed never seen before, parallel computing is becoming more and more essential to process this massive volume of data in a timely manner. Therefore, recently, concurrent computations have been receiving increasing attention due to the widespread adoption of multi-core processors and the emerging advancements of cloud computing(More)
VERITAS employs a 12m segmented mirror and pixellated photomultiplier tube camera to detect the brief pulse of Cherenkov radiation produced by the extensive air shower initiated by a cosmic high-energy gamma ray. The VERITAS data acquisition system consists of a 500 Mega-Sample-PerSecond custom-built flash ADC system, which samples the Cherenkov light pulse(More)