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Comparison of the behavioral and cardiovascular effects of mephedrone with other drugs of abuse in rats

• Kurt J Varner, Kyle Daigle, +4 authors Peter John Winsauer
• Psychopharmacology
• 2012

Exceedingly little experimental research exists on the popular recreational drug mephedrone (4-methylmethcathinone) despite clinical reports concerning its behavioral and cardiovascular toxicity. To… (More)

Effects of pregnanolone and dehydroepiandrosterone on ethanol intake in rats administered ethanol or saline during adolescence.

• Olga V. Gurkovskaya, Stuart T Leonard, Peter B. Lewis, Peter John Winsauer
• Alcoholism, clinical and experimental research
• 2009

BACKGROUND Adolescent alcohol use may contribute to long-term changes in the receptors and neuroactive steroids that may mediate its effects and to subsequent alcohol abuse and dependence as an… (More)

Tolerance to chronic delta-9-tetrahydrocannabinol (Δ⁹-THC) in rhesus macaques infected with simian immunodeficiency virus.

• Peter John Winsauer, Patricia E. Molina, +10 authors Peter B. Lewis
• Experimental and clinical psychopharmacology
• 2011

Although Δ⁹-THC has been approved to treat anorexia and weight loss associated with AIDS, it may also reduce well-being by disrupting complex behavioral processes or enhancing HIV replication. To… (More)

Effects of positive and negative modulators of the γ-aminobutyric acid A receptor complex on responding under a differential-reinforcement-of-low-rate schedule of reinforcement in rats.

• Russell Joseph Amato, Peter B. Lewis, Hongbo He, Peter John Winsauer
• Behavioural pharmacology
• 2010

Relatively little is known about the behavioral effects of the neurosteroids compared with other drugs that modulate the γ-aminobutyric acid A (GABAA) receptor complex. This study examined the acute… (More)

Effects of 7-keto dehydroepiandrosterone on voluntary ethanol intake in male rats.

• Mary E Worrel, Olga V. Gurkovskaya, Stuart T Leonard, Peter B. Lewis, Peter John Winsauer
• Alcohol
• 2011

Administration of dehydroepiandrosterone (DHEA), a neurosteroid that can negatively modulate the GABA A receptor, has been shown to decrease voluntary intake of ethanol in rats. In vivo, DHEA can be… (More)

Leveraging Appreciative Intelligence for Positive Enactment in Times of Uncertainty: A Case Study of a Small Investment Firm

• Peter B. Lewis
• 2010

Problem statement: How do we develop a complex understanding of marke ts and environments? Are markets and environments concrete en ities that exist “out there” or are they socially constructed by… (More)

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