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PURPOSE Former studies have found rates of endogenous endophthalmitis ranging from 0% to 37% in patients with fungemia. This study sought to prospectively determine the rate and risk factors for endogenous chorioretinitis and endophthalmitis in patients with fungemia. METHODS A prospective cohort study was performed of consecutive adult inpatients at a(More)
BACKGROUND AND OBJECTIVE Aflibercept is a vascular endothelial growth factor (VEGF) inhibitor recently approved by the U.S. Food and Drug Administration for the treatment of diabetic macular edema (DME). Currently, the effect of switching to aflibercept from other anti-VEGF agents for DME is unknown. PATIENTS AND METHODS In this prospective,(More)
A previously healthy 7-week-old boy developed bilateral central retinal artery occlusions in the presence of hyperhomocysteinemia and elevated serum methylmalonic acid and was found to have a transcobalamin receptor mutation. Retinal arterial occlusion is uncommon in young patients and typically prompts a systemic workup. In cases of atypical retinal(More)
PURPOSE To review the effect of green diode laser ablation therapy on retinal structure and functional outcome in patients with advanced Coats disease. DESIGN Retrospective, interventional case series. METHODS Fourteen eyes of 13 patients with Coats disease were included in this study. Medical records, Retcam photographs (Clarity Medical Systems,(More)
Incontinentia pigmenti (IP) is a rare syndrome with skin lesions, ocular abnormalities in the retina and elsewhere, central nervous system abnormalities, and teeth defects. The authors present an updated review of the literature, highlighting diagnosis, epidemiology, pathophysiology, clinical features, and management of IP. IP is an X-linked dominant(More)
BACKGROUND AND OBJECTIVE Subthreshold retinal laser therapy is efficacious for a variety of retinovascular disorders. Currently, it is unknown which laser parameters can ensure no detectable damage to human retina tissue. MATERIALS AND METHODS One informed physician participant with a normal retina was treated with three levels (75%, 50%, and 25%) of(More)
Factors predictive for response of diabetic macular edema (DME) to intravitreal bevacizumab (IVB) remain unclear. In this study, we assess the predictability of DME response to IVB based on the response to IVB in a previously treated fellow eye and other known pre-injection factors in (DME). Retrospective chart review was conducted on 28 patients (56 eyes)(More)
PURPOSE A 67-year-old man with an embolic branch retinal artery occlusion occurring as a complication of internal carotid artery stenting, despite the use of a distal filter cerebral protection device was reported. METHODS Observational case report. One patient case is included in this case report. RESULTS The patient developed a branch retinal arterial(More)
BACKGROUND We report the case of an 81-year-old woman with a history of radial keratotomy 9 years prior who developed endophthalmitis without preceding keratitis 4 days after uneventful photorefractive keratectomy surgery. This case report utilized clinical examination and microbacterial laboratory findings. FINDINGS Diagnosis of bacterial endophthalmitis(More)
PRESENTATION We present multi‑modal imaging of two phakic patients who developed lens nucleus dislocation following multiple complicated vitrectomy surgeries. We feel vitreoretinal physicians should be aware of this phenomenon and its presentation. To the best of our knowledge, high‑quality multi‑modal imaging of this presentation has not been published.(More)