Sort by:

• Highly Influential Citations
• Citations
• Acceleration
• Velocity
• Recency

Learn More

Crystal structure and mechanism of human lysine-specific demethylase-1

• Pete Stavropoulos, Günter Blobel, André Hoelz
• Nature Structural &Molecular Biology
• 2006

The reversible methylation of specific lysine residues in histone tails is crucial in epigenetic gene regulation. LSD1, the first known lysine-specific demethylase, selectively removes monomethyl and… (More)

Architecture of a Coat for the Nuclear Pore Membrane

• Kuo-Chiang Hsia, Pete Stavropoulos, Günter Blobel, André Hoelz
• Cell
• 2007

The symmetric core of the nuclear pore complex can be considered schematically as a series of concentric cylinders. A peripheral cylinder coating the pore membrane contains the previously… (More)

Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand

• Almudena R Ramiro, Pete Stavropoulos, Mila Jankovic, Michel C. Nussenzweig
• Nature Immunology
• 2003

Somatic hypermutation and class switch recombination are DNA modification reactions that alter the genes encoding antibodies in B lymphocytes. Both of these distinct reactions require… (More)

Somatic Hypermutation Is Limited by CRM1-dependent Nuclear Export of Activation-induced Deaminase

• Kevin M McBride, Vasco M. Barreto, Almudena R Ramiro, Pete Stavropoulos, Michel C. Nussenzweig
• The Journal of experimental medicine
• 2004

Somatic hypermutation (SHM) and class switch recombination (CSR) are initiated in activated B lymphocytes by activation-induced deaminase (AID). AID is thought to make lesions in DNA by deaminating… (More)

Molecular basis for the autoregulation of the protein acetyl transferase Rtt109.

• Pete Stavropoulos, V Endre Nagy, Günter Blobel, André Hoelz
• Proceedings of the National Academy of Sciences…
• 2008

Rtt109 is a protein acetyltransferase (PAT) that is responsible for the acetylation of lysine-56 of histone 3 (H3K56) in yeast. H3K56 acetylation has been implicated in the weakening of the… (More)

Using T. brucei as a biological epitope-display platform to elicit specific antibody responses.

• Pete Stavropoulos, F. Nina Papavasiliou
• Journal of immunological methods
• 2010

The African trypanosome (Trypanosoma brucei) is transmitted by the bite of the tsetse vector to the mammalian bloodstream where it exists as a completely extracellular parasite. As a result of this… (More)

Lysine-specific demethylase 1 as a potential therapeutic target.

• Pete Stavropoulos, André Hoelz
• Expert opinion on therapeutic targets
• 2007

Chromatin is a highly dynamic structure that undergoes a variety of chemical modifications. These modifications mediate alterations of the chromatin architecture, generate binding platforms that are… (More)

A glutamate/aspartate switch controls product specificity in a protein arginine methyltransferase.

• Erik W Debler, Kanishk Jain, +4 authors Pete Stavropoulos
• Proceedings of the National Academy of Sciences…
• 2016

Trypanosoma brucei PRMT7 (TbPRMT7) is a protein arginine methyltransferase (PRMT) that strictly monomethylates various substrates, thus classifying it as a type III PRMT. However, the molecular basis… (More)

• ‹
• 1
• ›