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During the past several years, there has been tremendous progress on the development of the RF system and accelerating structures for a Next Linear Collider (NLC). Developments include high-power klystrons, RF pulse compression systems and damped/detuned accelerator structures to reduce wakefields. In order to integrate these separate development efforts(More)
When chemotherapy is used in androgen-independent prostate cancer (AIPC), androgen deprivation is continued despite its failure. In this study, we investigated whether it was possible to re-induce hormone sensitivity in previously castrate patients by stopping endocrine therapy during chemotherapy. A phase II prospective study investigated the effects of(More)
The final focus of the Next Linear Collider (NLC) demag-nifies electron and positron beams of 250–750 GeV energy down to a transverse size of about 2.5 × 350 nm 2 at the interaction point (IP). The basic layout, momentum band-width, vibration tolerances, wakefield effects, and the tun-ability of the proposed final focus design are discussed. Also a(More)
Renal cell carcinoma (RCC) is notoriously chemoresistant. Current management of metastatic disease usually includes immunological agents of which the most clearly evaluated is alpha interferon. Following the failure of such agents no clear second-line therapy exists. The use of a novel combination of cisplatin, irinotecan and mitomycin may offer some(More)
The linacs proposed for the Next Linear Collider (NLC) and Japanese Linear Col-lider (JLC) would contain several thousand X-Band accelerator structures that would operate at a loaded gradient of 50 MV/m. An extensive experimental and theoretical program is underway at SLAC, FNAL and KEK to develop structures that reliably operate at this gradient. The(More)
PURPOSE To determine the feasibility of induction chemotherapy and chemo-IMRT in head and neck squamous cell cancers at risk of bilateral nodal spread (midline tumours) and to evaluate whether bilateral superficial lobe parotid-sparing IMRT can reduce the incidence of ⩾G2 subjective xerostomia. METHODS Patients with midline tumours were enrolled to a(More)
Almost all the electricity currently produced in the UK is generated as part of a centralised power system designed around large fossil fuel or nuclear power stations. This power system is robust and reliable but the efficiency of power generation is low, resulting in large quantities of waste heat. The principal aim of this paper is to investigate an(More)
We establish the existence of the top quark using a 67 pb ' data sample of pp collisions at ~s = 1.8 TeV collected with the Collider Detector at Fermilab (CDF). Employing techniques similar to those we previously published, we observe a signal consistent with tt decay to WWbb, but inconsistent with the background prediction by 4.8o.. Additional evidence for(More)