Perrine Marec

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Dysregulated cell growth or differentiation due to misexpression of developmental critical factors seems to be a decisive event in oncogenesis. As osteosarcomas are histologically defined by malignant osteoblasts producing an osteoid component, we prospected in pediatric osteosarcomas treated with OS94 protocol the genomic status of several genes implied in(More)
This in vitro study introduces a new method to determine quantitative parameters characterizing the mechanical behaviour of the costo-vertebral joint. These parameters are useful in building numerical models of the thoracic spine, taking into account the thoracic cage. Nine thoracic cages were isolated from fresh human cadavers. From each cage, three(More)
Chronic pain is usually underestimated in children, due to lack of knowledge and its specific signs. In addition to suffering, chronic pain causes a physical, psychological, emotional, social, and financial burden for the child and his family. Practitioners may find themselves in a situation of failure with depletion of medical resources. Some types of(More)
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