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UNLABELLED In this clinical, randomized, prospective study, we compared the effects of three different analgesia techniques (thoracic epidural analgesia [TEA] with and without preoperative initiation and IV patient-controlled analgesia [IV-PCA]) on postthoracotomy pain in 69 patients. In two groups, a thoracic epidural catheter was inserted preoperatively.(More)
INTRODUCTION In this prospective, randomized controlled study, we aimed to evaluate the effect of IgM-enriched immunoglobulin treatment on progression of organ failure and septic shock in patients with severe sepsis. MATERIALS AND METHODS Forty-two patients with severe sepsis were enrolled in the study. Patients in the study group (n = 21) received an(More)
Aspiration pneumonia due to gastroesophageal reflux is a frequent complication in ICU. The most commonly chosen method for long-term enteral access is gastrostomy and this method also reduces the risk of aspiration and shortens the hospital stay. We evaluated 31 patients in whom PEG was performed between 1997-98 in our unit. Indication of PEG was long-term(More)
OBJECTIVE To investigate whether the response to sustained inflation and postinflation positive end-expiratory pressure varies between acute respiratory distress syndrome with pulmonary (ARDS(exp)) and extrapulmonary origin (ARDS(exp)). DESIGN Prospective clinical study. SETTING Multidisciplinary intensive care unit in a university hospital. PATIENTS(More)
OBJECTIVE High peak airway opening pressures (Pao) are used routinely during recruitment maneuvers to open collapsed lung units. High peak Pao, however, can cause lung injury as evidenced by translocation of intratracheally inoculated bacteria. In this study we explored whether recruitment maneuvers that used high Pao could cause translocation of the(More)
INTERVENTIONS The effects of immunoglobulin G and immunoglobulins enriched with immunoglobulin A and immunoglobulin M on blood-brain barrier integrity and survival rates in septic rats were comparatively investigated. MEASUREMENTS Sepsis was induced by cecal ligation and perforation in Sprague-Dawley rats. The animals were divided into the following(More)
OBJECTIVE The purpose of this study was to investigate the effect of magnesium sulfate on pain management for post-thoracotomy patients. DESIGN A prospective, randomized, controlled clinical study. SETTING University hospital. PARTICIPANTS Twenty-four patients undergoing thoracotomy. INTERVENTIONS After thoracotomy operations, patients were assigned(More)
OBJECTIVE The aim of this study was to follow critically ill patients prospectively in intensive care units (ICUs) to determine risk factors for mortality and outcome associated with nosocomial bacteraemia (NB). SUBJECTS AND METHODS A case-control study of 176 patients was conducted to identify the risk factors for mortality of NB in ICU patients. The(More)
OBJECTIVE To evaluate the time course of Pao2 change following the setting of optimal positive end-expiratory pressure (PEEP) in patients with acute respiratory distress syndrome (ARDS). DESIGN Prospective clinical study. SETTING Multidisciplinary intensive care unit of a university hospital. PATIENTS Twenty-five consecutive patients with ARDS. (More)
Procalcitonin (PCT) is increasingly recognised as an important diagnostic parameter in clinical evaluation of the critically ill. This prospective study was designed to investigate PCT as a diagnostic marker of infection in critically ill patients with sepsis. Eighty-five adult ICU patients were studied. Four groups were defined on the basis of clinical,(More)