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cis-Dichlorodiammineplatinum(II) (DDP) was studied in 16 children with far-advanced malignancies. Three dosage schedules were tried: regimen A, 20 mg/m2/day x 5 days for 3-4 weeks (11 patients); regimen B, 50 mg/m2 once a week (four patients); and regimen C, 60 mg/m2/day x 2 days every 3-4 weeks (one patient). Four of 16 patients (25%) showed partial… (More)
40 cases of breast malignancy constituted the study group and 10 sex matched formed the control grp. Serum level of copper was estimated by atomic absorption photometry and ceruloplasmin was done by Houchin's method. The study group showed significant hypercupremia and increased level of serum ceruloplosmin. It was postulated that levels copper and… (More)
A 5-month-old female infant presented with new-onset acute lymphoblastic leukemia and hyperleukocytosis with white blood cell count of 352 × 10(9) cells/L. She developed sinus pauses and hypoxemic respiratory failure. A manual single volume exchange blood transfusion was done with complete resolution of sinus pauses and hypoxemia.