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- Carlos Balmaceda, Gabriella T. Heller, +8 authors Jesualdo Finlay
- Journal of clinical oncology : official journal…
- 1996
PURPOSE
Radiation therapy for CNS germ cell tumors (GCT) is commonly associated with neurologic sequelae. We designed a therapeutic trial to determine whether irradiation could be avoided.
PATIENTS… (More)
- S. Tan, M. Wood, Penny Maher
- Journal of neurochemistry
- 1998
Oxidative stress is implicated in a number of neurological disorders including stroke, Parkinson's disease, and Alzheimer's disease. To study the effects of oxidative stress on neuronal cells, we… (More)
- Penny Maher, James Davis
- The Journal of neuroscience : the official…
- 1996
Glutamate kills neuronal cells by either a receptor-mediated pathway or the inhibition of cystine uptake, the "oxidative pathway." Antioxidants can block cell death initiated by either pathway,… (More)
- James Davis, Penny Maher
- Brain research
- 1994
A neuronal cell line, HT-22, is sensitive to glutamate cytotoxicity via a non-receptor mediated oxidative pathway. 12-O-tetradecanoylphorbol-13-acetate (TPA), an activator of protein kinase C, blocks… (More)
- Michal K. Stachowiak, John R. Moffett, Penny Maher, Johannes Tucholski, Ewa K. Stachowiak
- Molecular Neurobiology
- 1997
This article discusses a novel intracrine mechanism of growth-factor action in the nervous system whereby fibroblast growth factor-2 (FGF-2) and its receptor accumulate in the cell nucleus and act as… (More)
- S. Tan, Dominic Schubert, Penny Maher
- Current topics in medicinal chemistry
- 2001
Extensive nerve cell death occurs during the development of the central nervous system as well as in episodes of trauma and in neurodegenerative disease. The mechanistic details of how these cells… (More)
- Dominic Schubert, H. Kimura, Penny Maher
- Proceedings of the National Academy of Sciences…
- 1992
The sympathetic nerve cell line PC-12 is killed by glutamate in a concentration-dependent manner. Although glycine and the deletion of magnesium weakly potentiate glutamate toxicity and PC-12 cells… (More)
- Hao Peng, John R. Moffett, +9 authors Michal K. Stachowiak
- Molecular biology of the cell
- 2001
In bovine adrenal medullary cells synergistically acting type 1 and type 2 angiotensin II (AII) receptors activate the fibroblast growth factor-2 (FGF-2) gene through a unique AII-responsive promoter… (More)
- Charles R Dean, Lipeng Wang, +12 authors P. Kim
- Nature
- 2013
Electrons moving through a spatially periodic lattice potential develop a quantized energy spectrum consisting of discrete Bloch bands. In two dimensions, electrons moving through a magnetic field… (More)
- Yasuaki Sagara, Richard Dargusch, David Chambers, J. Davis, Dominic Schubert, Penny Maher
- Free radical biology & medicine
- 1998
Oxidative stress is implicated in several pathologies such as AIDS, Alzheimer's disease, and Parkinson's disease, as well as in normal aging. As a model system to study the response of cells to… (More)