Comparative and phylogenomic studies on the mitochondrial genomes of Pentatomomorpha (Insecta: Hemiptera: Heteroptera)
Heteropteran insects are extremely complex groups worthy of further study because of the unusual tetranucleotide initiation codon and their great mt-genomic diversity, including gene rearrangements and recombinations.
Phylogenetic analysis of the true water bugs (Insecta: Hemiptera: Heteroptera: Nepomorpha): evidence from mitochondrial genomes
- Jimeng Hua, Ming Li, Pengzhi Dong, Ying Cui, Q. Xie, W. Bu
- BiologyBMC Evolutionary Biology
- 15 June 2009
The mt-genome is an effective data source for resolving intraordinal phylogenetic problems at the superfamily level within Heteroptera and the Pleoidea is not a member of the Nepomorpha and Aphelocheiroidea should be grouped back into NaucoroideA.
PD-L1 Expression Is Associated with Tumor FOXP3+ Regulatory T-Cell Infiltration of Breast Cancer and Poor Prognosis of Patient
The results suggest that PD-L1 and FOXP3+Tregs may work synergistically and their up-regulated expressions promote tumor immune evasion in breast cancer.
Mitochondrial genome of one kind of giant Asian mantis, Hierodula formosana (Mantodea: Mantidae)
- Xiaoxuan Tian, Jie Liu, Ying Cui, Pengzhi Dong, Yan Zhu
- BiologyMitochondrial DNA. Part A, DNA mapping…
- 2 January 2017
The complete mitochondrial genome of H. formosana is investigated and an extra non-coding region is inserted between trnM and ND2, similar to the other Mantidae species T. tamolana.
Identification of Key Genes and Pathways in Triple-Negative Breast Cancer by Integrated Bioinformatics Analysis
- Pengzhi Dong, Bing Yu, Lanlan Pan, Xiaoxuan Tian, Fangfang Liu
- BiologyBioMed Research International
- 2 August 2018
SOX8, AR, C9orf152, NRK and RAB30, and other key genes and pathways might be promising targets for the TNBC treatment.
The mitochondrial genome of Protohermes concolorus Yang et Yang 1988 (Insecta: Megaloptera: Corydalidae)
The phylogenetic analyses based on all the 13 protein genes showed that Megaloptera was the sister group of other holometabolous insects except Coleoptera.
Two novel lncRNAs discovered in human mitochondrial DNA using PacBio full-length transcriptome data
A general framework to use PacBio full-length transcriptome sequencing for the investigation of the fundamental problems in mitochondrial biology, e.g. genome arrangement, heteroplasmy, RNA processing and the regulation of transcription or replication is introduced.
Hawthorn (Crataegus pinnatifida Bunge) leave flavonoids attenuate atherosclerosis development in apoE knock-out mice.
Danshensu Promotes Cholesterol Efflux in RAW264.7 Macrophages
This work reported on the heretofore unknown therapeutic effect of Danshensu (DSS) in reducing intracellular cholesterol level and unraveled the mechanism of DSS promotes cholesterol efflux, which significantly reduced scavenger receptor CD36 and its orthologue SR-BI.
Identification of Key Pathways and Genes in Advanced Coronary Atherosclerosis Using Bioinformatics Analysis
- Xiaowen Tan, Xiting Zhang, Lanlan Pan, Xiaoxuan Tian, Pengzhi Dong
- Biology, MedicineBioMed Research International
- 31 October 2017
Analysis of DEGs would make a deeper understanding of the molecular mechanisms of Atherosclerosis development and they might be used as molecular targets and diagnostic biomarkers for the treatment of atherosclerosis.