Pengfei Zheng

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Hepatocellular carcinoma (HCC) is one of the most common internal malignant tumors. Glypican-3 (GPC3) is involved in the biological and molecular events in the tumorigenesis of HCC. We used RNA interference to evaluate the molecular effects of GPC3 suppression at the translational level and demonstrated for the first time that GPC3 silencing results in a(More)
The occurrence of 14 polycyclic aromatic hydrocarbons (PAHs) listed by the United States Environmental Protection Agency was investigated in surface seawater of Yangpu Bay, China in November 2013 (winter) and May 2014 (summer). Seventy-two samples were collected from 12 sampling sites. The total concentrations of PAHs in Yangpu Bay showed obvious variations(More)
Oncostatin M (OSM) exhibits many unique biological activities by activating the Oβ receptor. However, its role in myocardial ischemia/reperfusion injury (I/R injury) in mice remains unknown. We investigated whether Notch3/Akt signaling is involved in the regulation of OSM-induced protection against cardiac I/R injury. The effects of OSM were assessed in(More)
Modern applications especially cloud-based or cloud-centric applications always have many components running in the large distributed environment with complex interactions. They are vulnerable to suffer from performance or availability problems due to the highly dynamic runtime environment such as resource hogs, configuration changes and software bugs. In(More)
An approach based on Virtual Partition is proposed to improve the load balance in Reduce phase in MapReduce-based system in cloud computing. After each Map task finished, the output keys are partitioned to different virtual partitions according to Hash Function. And LBVP (a load balance algorithm based on continuous virtual partition) is designed to combine(More)
Benzo(a)pyrene and dichlorodiphenyltrichloroethane are typical persistent organic pollutants, and also the widespread environmental estrogens with known toxicity towards green mussels Perna viridis. In this study, the toxicological effects of BaP and DDT and their mixture were assessed in green mussel gonads using proteomic and metabolomic approaches.(More)
TreeGenes and tree fruit Genome Database Resources serve the international forestry and fruit tree genomics research communities, respectively. These databases hold similar sequence data and provide resources for the submission and recovery of this information in order to enable comparative genomics research. Large-scale genotype and phenotype projects have(More)
Software systems continuously running over a long time may suffer gradual performance degradation or failure rate increasing. This phenomenon, known as "Software Aging", has become a great challenge to dependability-critical software systems. Researchers have made remarkable achievements in predicting resource exhaustion time and designing optimal(More)
Pyrene, a typical polycyclic aromatic hydrocarbon, is a common pollutant in the marine environment. Polycyclic aromatic hydrocarbons initiate cellular detoxification in an exposed organism via the activation of the aryl hydrocarbon receptor (AhR). Subsequent metabolism of these xenobiotics is mainly by the cytochrome P450 enzymes of the phase I(More)