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In nature, self-assembling and disassembling complexes of proteins and nucleic acids bound to a variety of ligands perform intricate and diverse dynamic functions. In contrast, attempts to rationally encode structure and function into synthetic amino acid and nucleic acid sequences have largely focused on engineering molecules that self-assemble into(More)
This paper proposes a selective data pruning-based compression scheme to improve the rate-distortion relation of compressed images and video sequences. The original frames are pruned to a smaller size before compression. After decoding, they are interpolated back to their original size by an edge-directed interpolation method. The data pruning phase is(More)
Programmed self-assembly of strands of nucleic acid has proved highly effective for creating a wide range of structures with desired shapes. A particularly successful implementation is DNA origami, in which a long scaffold strand is folded by hundreds of short auxiliary strands into a complex shape. Modular strategies are in principle simpler and more(More)
OBJECTIVE The Chinese population has been aging rapidly and the country's economy has experienced exponential growth during the past three decades. The goal of this study was to estimate the changes in the prevalence of dementia, Alzheimer's disease (AD), and vascular dementia (VaD) among elderly Chinese individuals and to analyze differences between urban(More)
We describe a computational model for studying the complexity of self-assembled structures with active molecular components. Our model captures notions of growth and movement ubiquitous in biological systems. The model is inspired by biology's fantastic ability to assemble biomolecules that form systems with complicated structure and dynamics, from(More)
Block-based motion and disparity compensation are popular techniques to exploit correlation between video frames. Block sizes used for compensation can be chosen to achieve a good trade-off between signaling overhead and prediction accuracy. However, motion field boundaries correspond to objects having arbitrary shapes; this limits the accuracy of(More)
The self-assembly process for bottom-up construction of nanostruc-tures is of key importance to the emerging scientific discipline Nanoscience. However, self-assembly at the molecular scale is prone to a quite high rate of error. Such high error rate is a major barrier to large-scale experimental implementation of DNA tiling. The goals of this paper are to(More)
A nanoscale object moving autonomously over a self-assembled microscopic structure has important nano-robotics applications, e.g. serving as a nano-particle and/or information carrier. Recent successes in self-assembly of DNA nanostructures provide a solid structural basis to meet this challenge. However, existing nanoscale synthetic DNA devices are(More)