Peng-Jun Zhao

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Polyphyllins, a major component of Rhizoma paridis, have been extensively used in non-small cell lung cancer (NSCLC). The aim of the present study was to evaluate the effects of Paris saponin I (PSI) on a panel of gefitinib-resistant NSCLC cell lines and its inhibition of tumor growth in a nude mouse model. The MTT assay was used to assess growth(More)
  • Peng-Jun Zhao
  • 2010 International Conference on Computational…
  • 2010
In the paper a novel harmony search (HS) algorithm based on opposition and differential evolution (ODHS) algorithm is proposed in order to solve high dimensional optimization problems. It provides a new architecture of hybrid algorithms, which organically merges the differential evolution (DE) into HS algorithm and the ODHS algorithm initializes the HM(More)
Acquired resistance to epidermal growth factor inhibitors has been reported to be associated with cross‑resistance to radiation. Paris Saponins (PSs) exert a wide range of pharmacological activities, including cell apoptosis induction, multidrug resistance inhibition, angiogenesis inhibition and tumor cell migration by modulating various signaling pathways.(More)
This paper presents an improved differential evolution algorithm with adaptive mutation and control parameters (IADE) for global numerical optimization over continuous space. In the IADE algorithm, scaling factor F and crossover rate CR are adaptive various by using the previous learning experience, the target individuals will be mutation by the population(More)
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