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Popular online social networks (OSNs) like Facebook and Twitter are changing the way users communicate and interact with the Internet. A deep understanding of user interactions in OSNs can provide important insights into questions of human social behavior and into the design of social platforms and applications. However, recent studies have shown that a(More)
Similar to software bugs, configuration errors are also one of the major causes of today's system failures. Many configuration issues manifest themselves in ways similar to software bugs such as crashes, hangs, silent failures. It leaves users clueless and forced to report to developers for technical support, wasting not only users' but also developers'(More)
The reduced expression in immortalized cells (REIC)/Dickkopf (Dkk)-3, a member of the Dkk gene family, is a tumor suppressor in a broad range of cancers. REIC/Dkk-3 transfected stable clones of mouse prostate cancer RM9 cells (RM9-REIC) and the empty vector-transfected control clone cells (RM9-EV) were established. Clones were used to evaluate the(More)
When systems fail in the field, logged error or warning messages are frequently the only evidence available for assessing and diagnosing the underlying cause. Consequently , the efficacy of such logging—how often and how well error causes can be determined via postmortem log messages—is a matter of significant practical importance. However, there is little(More)
As software evolves, problematic changes can significantly degrade software performance, i.e., introducing performance regression. Performance regression testing is an effective way to reveal such issues in early stages. Yet because of its high overhead, this activity is usually performed infrequently. Consequently, when performance regression issue is(More)
Early detection is the key to minimizing failure damage induced by configuration errors, especially those errors in configurations that control failure handling and fault tolerance. Since such configurations are not needed for initialization, many systems do not check their settings early (e.g., at startup time). Consequently, the errors become latent until(More)
UNLABELLED Radioimmunotherapy is approved by the Food and Drug Administration for CD20 antigen-positive follicular and transformed non-Hodgkin lymphoma. The goal of this study was to obtain the opinion of hematologists and medical oncologists about CD20-directed radioimmunotherapy in the United States. METHODS An e-mail-based survey with 8 questions was(More)
A multifunctional theranostic platform based on photosensitizer-loaded plasmonic vesicular assemblies of gold nanoparticles (GNPs) is developed for effective cancer imaging and treatment. The gold vesicles (GVs) composed of a monolayer of assembled GNPs show strong absorbance in the near-infrared (NIR) range of 650-800 nm, as a result of the plasmonic(More)
Photodynamic therapy (PDT) has emerged as an alternative and promising noninvasive treatment for cancer as well as non-cancer diseases, which involves the uptake of photosensitizers (PSs) by cancer cells followed by irradiation. The use of nanomaterials as carriers of PSs is a very promising approach to improve the development of PDT in clinical medicine.(More)
The hierarchical assembly of gold nanoparticles (GNPs) allows the localized surface plasmon resonance peaks to be engineered to the near-infrared (NIR) region for enhanced photothermal therapy (PTT). Herein we report a novel theranostic platform based on biodegradable plasmonic gold nanovesicles for photoacoustic (PA) imaging and PTT. The disulfide bond at(More)