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BACKGROUND Keratoconus (KC) is a complex degenerative disorder of the cornea. Genetic, environmental, and lifestyle factors may all contribute to the pathogenesis of KC. Most of the reported KC-associated SNPs have been detected in Caucasians and Australians. To investigate whether the reported associated SNPs can be found in a Chinese population, we(More)
Stenotrophomonas maltophilia is an important global opportunistic pathogen for which limited therapeutics are available because of the emergence of multidrug-resistant strains. A novel bacteriocin, maltocin P28, which is produced by S. maltophilia strain P28, may be the first identified phage tail-like bacteriocin from S. maltophilia. Maltocin P28 resembles(More)
Corneal fibroblasts exhibit different phenotypes in different phases of corneal wound healing. In the inflammatory phase, the cells assume a proinflammatory phenotype and produce large amounts of cytokines and chemokines, but in the proliferative and remodeling phases, they adapt a profibrotic state, differentiate into myofibroblasts and increase(More)
In this paper, time series model of ARIMA is used to make short-term forecasting of property crime for one city of China. With the given data of property crime for 50 weeks, an ARIMA model is determined and the crime amount of 1 week ahead is predicted. The modelpsilas fitting and forecasting results are compared with the SES and HES. It is shown that the(More)
Most current chatbot engines are designed to reply to user utterances based on existing utterance-response (or Q-R)1 pairs. In this paper, we present DocChat, a novel information retrieval approach for chatbot engines that can leverage unstructured documents, instead of Q-R pairs, to respond to utterances. A learning to rank model with features designed at(More)
4581 Background: ABT-869 is a novel orally active, potent and selective inhibitor of the vascular endothelial growth factor and platelet derived growth factor families of receptor tyrosine kinases. Results of an interim analysis of a phase 2 trial of ABT-869 in HCC are presented. METHODS An open-label, multicenter phase II trial (M06-879) of oral ABT-869(More)
BACKGROUND & AIMS Alcoholic liver disease is a leading cause of mortality. Chronic alcohol consumption is accompanied by intestinal dysbiosis, and development of alcoholic liver disease requires gut-derived bacterial products. However, little is known about how alterations to the microbiome contribute to pathogenesis of alcoholic liver disease. METHODS We(More)
The ultimate goal of both game developers and network engineers is to provide a satisfactory quality of experience (QoE) for players. Most past works resort the subjective approaches to assess QoE which have serious limitations. But because of the interdependency of the quality metrics on game playability and the involvement of many players' subjective(More)