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Multicomponent synthesis of 6H-dibenzo[b,d]pyran-6-ones and a total synthesis of cannabinol.
TLDR
A multicomponent domino reaction that affords 6H-dibenzo[b,d]pyran-6-ones is reported, and the yields are considerably better than those obtained using a stepwise process. Expand
Synthesis of 6H-dibenzo[b,d]pyran-6-ones using the inverse electron demand Diels-Alder reaction.
A set of coumarin-fused electron-deficient 1,3-dienes was synthesized, which differ in the nature of the electron-withdrawing group (EWG) at the terminus of the diene unit and (when EWG = CO(2)Me)Expand
Olefination Reactions in the Synthesis of Cyclophanes
A survey of olefination reactions that have been used in the synthesis of cyclophanes is presented. This covers the Ramberg–Backlund reaction, the Wittig and related reactions, the McMurry andExpand
Concise, aromatization-based approach to an elaborate C2-symmetric pyrenophane.
A very short synthesis (5 steps), the crystal structure and resolution of an elaborate, inherently chiral [n](1,6)pyrenophane is reported. The synthesis hinges upon two very productive events: aExpand
An inverse electron demand Diels-Alder-based total synthesis of defucogilvocarcin V and some C-8 analogues.
TLDR
A concise total synthesis of defucogilvocarcin V is reported, featuring the formation of the C-ring using a vinylogous Knoevenagel/transesterification reaction and construction of the D-ring by way of an inverse electron demand Diels-Alder-driven domino reaction. Expand
Synthesis of 6H‐Dibenzo[b,d]pyran‐6‐ones Using the Inverse Electron Demand Diels—Alder Reaction.
In some cases, the dihydro analogues are obtained which can smoothly be converted into the title compounds by treatment with DDQ.
Concise, Aromatization-Based Approach to an Elaborate C2-Symmetric Pyrenophane.
Two successive intramolecular McMurry reactions of tetraaldehyde (V) and a subsequent valence isomerization/dehydrogenation reaction afford the desired [12](1,6)pyrenophane derivative (VI) in lowExpand
Inverse electron demand diels-alder based approach to 6H-Dibenzo[b, d]pyran-6-ones and its application in target-oriented synthesis
This thesis deals with the exploration and the development of Inverse Electron-Demand Diels-Alder (IEDDA)-based methodologies to access 6H-dibenzo[b,d]pyran-6-ones (DBPs) and their application inExpand