Peixue Zhou

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Polychlorinated biphenyls (PCBs) are thought to cause adverse health effects, particularly endocrine disruption. However, results on the estrogenic activities of a large set of PCB congeners through hormone receptors have not been fully studied. In this study, we evaluated the anti/estrogenic effects of 20 PCBs using an in vitro dual-luciferase reporter(More)
There is a rising concern about the ecological safety and potential health risks caused by pesticides that are commonly present in the environment. Previous studies have shown that metabolites of pesticides sometimes possess more potent endocrine activity than the parent compounds. However very little efforts had been devoted to evaluate the environmental(More)
BACKGROUND Chiral insecticides significantly contribute to the environmental pollutions recently. As the development of industry and agriculture, increasing number of chiral insecticides are to be introduced into the market. However, their enantioselective toxicology to ecosystem still remains uncertain. METHODS In this review, we embarked on a structured(More)
The widespread use of pesticides, such as pyrethroids, increases health risks to non-target organisms. The potential toxicity of pyrethroids to the liver remains unclear and could be easily overlooked if only the common clinical indicators of liver disease are examined. In the present study, BALB/c mice were given intraperitoneal injections of 0, 2, 4, or 8(More)
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