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New polyacetylene glucosides from the florets of Carthamus tinctorius and their weak anti-inflammatory activities.
Eight new linear polyacetylene glucosides (1-8), containing two C(10)-, one C(13)- and five C(14)-acetylenes, together with three known polyacetylenes (9-11) were isolated from the florets ofExpand
Hepatoprotective activity of twelve novel 7'-hydroxy lignan glucosides from Arctii Fructus.
Twelve novel 7'-hydroxy lignan glucosides, including two benzofuran-type neolignans, two 8-O-4' neolignedans, and six tetrahydrofuranoid lignans were isolated from the fruit of Arctium lappa L. (Asteraceae), commonly known as Arctii Fructus and showed significantly stronger hepatoprotective activity than the positive control bicyclol. Expand
Forsythoneosides A-D, Neuroprotective Phenethanoid and Flavone Glycoside Heterodimers from the Fruits of Forsythia suspensa.
Forsythoneosides A-D (1-4), four unusual adducts of a flavonoid unit fused to a phenylethanoid glycoside through a pyran ring or carbon-carbon bond, and four new phenylethanoid glycosides (5-8) wereExpand
Acyl quinic acid derivatives from the stems of Erycibe obtusifolia.
Eleven new acyl quinic acid derivatives have been isolated from the stems of Erycibe obtusifolia together with eight known compounds and their structures were elucidated on the basis of spectroscopic data analysis and chemical evidence. Expand
Protective effects of Forsythia suspense extract with antioxidant and anti-inflammatory properties in a model of rotenone induced neurotoxicity.
FS8 protected dopamine neurons against rotenone toxicity via antioxidant and anti-inflammatory effects, which suggested the promising application of FS8 in the prevention and treatment of Parkinson disease. Expand
Two new quinochalcones from the florets of Carthamus tinctorius.
Two new quinochalcone compounds were isolated from the florets of Carthamus tinctorius and their unusual structures including their absolute stereochemistry were elucidated based on UV, IR, HRESIMS, 1D and 2D NMR data, and CD spectrum. Expand
Hepatoprotective glycosides from Leonurus japonicus Houtt.
When tested in in vitro assays, compounds 1, 2, 4, and 6 exhibited potent hepatoprotective activity against d-galactosamine-induced toxicity in HL-7702 cells at concentration of 1×10(-5) M. Expand
Polyflavanostilbene A, a new flavanol-fused stilbene glycoside from Polygonum cuspidatum.
Polyflavanostilbene A has an unprecedented rearranged flavanol skeleton fused to stilbenes via a hexahydrocyclopenta[c]furan moiety and showed strong inhibitory activity against α-glucosidase with an IC(50) value of 17.7 μM. Expand
New Hepatoprotective Coumarinolignoids from Mallotus apelta
Compounds 3 showed promising hepatoprotective activity against D‐galactosamine‐induced toxicity in WB‐F344 rat hepatic epithelial stem‐like cells and three new coumarinolignoids, malloapelins A–C, were isolated from the roots of Mallotus apelta Muell. Expand
An Efficient Method for Determining the Relative Configuration of Furofuran Lignans by 1H NMR Spectroscopy.
An efficient 1H NMR spectroscopic approach for determining the relative configurations of lignans with a 7,9':7',9-diepoxy moiety has been established and the rule should be applied carefully when the C-2 or C-6 substituent of the aromatic rings may alter the dominant conformers of the furofuran moiety. Expand