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Determination of protoberberine alkaloids in Rhizoma Coptidis by ERETIC ¹H NMR method.
TLDR
The high universality, accuracy, reproducibility, and efficiency of the ERETIC method demonstrated in this work suggest that this method could serve as a highly potential quantification alternative for quality assessment of TCM.
Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease.
TLDR
Three new lignans and three known compounds isolated from Kadsura longipedunculata showed appreciable inhibitory activity against HIV-1 protease with IC50 values of 50 and 20 microM, respectively.
(+)-12alpha-Hydroxysophocarpine, a new quinolizidine alkaloid and related anti-HBV alkaloids from Sophora flavescens.
TLDR
(+)-12alpha-Hydroxysophocarpine (8), a new quinolizidine alkaloid was isolated from the roots of Sophora flavescens and showed significant anti-HBV activity with inhibitory potency against HBsAg secretion at 48.3-79.3% and that against HBe Ag secretion at 24.6-34.6%.
Quinolizidine alkaloids with anti-HBV activity from Sophora tonkinensis.
TLDR
A new matrine-type alkaloid was isolated from the roots and rhizomes of Sophora tonkinensis Gapnep and showed potent anti-HBV activity with an inhibitory potency against HBsAg secretion and against HBeAg secretion.
Determination of quinolizidine alkaloids in Sophora medicinal plants by capillary electrophoresis
Abstract A new capillary electrophoresis (CE) method for the determination of quinolizidine alkaloids in Sophora medicinal plants was developed. A total of seven alkaloid components (cytisine,
Determination of quinolizidine alkaloids in Sophora tonkinensis by HPCE.
TLDR
The alkaloid constituents of authentic shan-dou-gen gave a specific HPCE electropherogram that could be used to distinguish the drug from potential substitutes and the content of oxymatrine and the total content of the seven quinolizidine alkaloids could be use as quantitative markers in order to assess the quality of S. tonkinensis.
Cytotoxic isoprenylated flavonoids from the roots of sophora flavescens.
Three new flavonoids, which are isoprenylated by fused 2,2-dimethyl-3,4-dihydro-2H-pyran moieties, were isolated from the roots of Sophora flavescens and named flavenochromanes A–C (1–3). Their
Three new isoprenylated flavonoids from the roots of Sophora flavescens
Three new flavonoids isoprenylated as 2,2-dimethyl-dihydropyran groups, named sophoranodichromanes A–C (1–3), have been isolated from the roots of Sophora flavescens, together with the known
Isoprenylated Flavonoids from the Roots and Rhizomes of Sophora tonkinensis
Two new flavanones, tonkinochromanes A (1) and B (2), and a new chalcone, tonkinochromane C (3), were isolated from the roots and rhizomes of Sophora tonkinensis. Their structures were elucidated by
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