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A mechanism involving evolutionary genetic programming (GP) and the expectation maximization algorithm (EM) is proposed to generate feature functions, based on the primitive features, for an image pattern recognition system on the diagnosis of the disease OPMD. Experiments show that the propose algorithm achieves an average performance of 90.20% recognition(More)
Aceruloplasminemia is an autosomal recessive disorder caused by mutations in the ceruloplasmin (CP) gene. It is characterized by iron accumulation in the brain and in visceral organs. However, little is known about the mechanism of iron transport in these regions. Adult CP null (CP(-/-)) mice show increased iron deposition in several regions of brain, such(More)
This study aims at developing new organoselenium compounds with good anticancer ability and low biotoxicity. Sucrose selenious ester (sucrose-Se) was synthesized by the reaction between sucrose and selenium oxychloride. MTT assay showed that sucrose-Se effectively inhibited the proliferation of cervical cancer cell line HeLa in a dose-dependent manner(More)
Two organoselenium compounds: xylitol selenious ester (xylitol-Se) and sucrose selenious ester (sucrose-Se) were synthesized, and their molecular structures were characterized in this study. In MTT assay, xylitol-Se and sucrose-Se showed cytostatic effects on human hepatocellular carcinoma cells SMMC-7221 in a dose-dependent manner, whereas they had no(More)
Hepcidin, a principle regulator of iron metabolism, is synthesized by the liver. Contradictory results have been reported on the regulation of hepcidin expression in response to serum transferrin saturation and liver iron content. In the present study, we explore the expression of murine hepcidin mRNA and further analyze the relationship between liver(More)
The purpose of this study is to explore an alternative means of hand image classification, one that requires minimal human intervention. The main tool for accomplishing this is a Genetic Algorithm (GA). This study is more than just another GA application; it introduces (a) a novel cooperative co-evolutionary clustering algorithm with dynamic clustering and(More)