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Localization is a fundamental and essential issue for wireless sensor networks (WSNs). Existing localization algorithms can be categorized as either range-based or range-free schemes. Range-based schemes are not suitable for WSNs because of their irregularity of radio propagation and their cost of additional devices. In contrast, range-free schemes do not(More)
Transcriptional activation of protective genes is mediated by a cis-acting element called the antioxidant responsive element (ARE). The transcription factor Nrf2 (NF-E2-related factor 2) binds to the ARE. Activation of this pathway protects cells from oxidative stress-induced cell death. Increased oxidative stress is associated with neuronal cell death(More)
Machine reading calls for programs that read and understand text, but most current work only attempts to extract facts from redundant web-scale corpora. In this paper , we focus on a new reading comprehension task that requires complex reasoning over a single document. The input is a paragraph describing a biological process , and the goal is to answer(More)
Astrocytes support neuronal antioxidant capacity by releasing glutathione, which is cleaved to cysteine in brain extracellular space. Free cysteine is then taken up by neurons through excitatory amino acid transporter 3 [EAAT3; also termed Slc1a1 (solute carrier family 1 member 1)] to support de novo glutathione synthesis. Activation of the nuclear factor(More)
The cyclin-dependent kinase Cdk5 and DARPP-32 (dopamine- and cAMP-regulated phosphoprotein of Mr 32 kDa)-dependent signaling have been implicated in the regulation of dopaminergic neurotransmission after chronic cocaine treatment. In this study, we examined if Cdk5 signaling participates in the behavioral and biochemical effect of acute and chronic(More)
Drug addiction represents a pathological form of neuroplasticity along with the emergence of aberrant behaviors involving a cascade of neurochemical changes mainly in the brain's rewarding circuitry. The aberrant behavioral phenotypes can be assessed by an animal model of drug-induced behavioral sensitization, which is characterized by an initiation stage(More)
The multiclass classification problem is considered and resolved through coding and regression. There are various coding schemes for transforming class labels into response scores. An equivalence notion of coding schemes is developed, and the regression approach is adopted for extracting a low-dimensional discriminant feature subspace. This feature subspace(More)
Crotamine, a 42-residue polypeptide derived from the venom of the South American rattlesnake Crotalus durissus terrificus, has been shown to be a cell-penetrating protein that targets chromosomes, carries plasmid DNA into cells, and shows specificity for actively proliferating cells. Given this potential role as a nucleic acid-delivery vector, we have(More)
As the Internet becomes more and more populous, people concern more about the copyright protection issue for digital data such as images and audio. Digital wa-termarking technique can hide data in images or audio to indicate the data owner or recipient. Therefore, it can protect the copyright. There were a lot of papers discussing how to embed watermark(More)