Pedro Toledo

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In a previous work, we studied the interaction of beta-amyloid fibrils (Abeta) with gold nanoparticles (AuNP) conjugated with the peptide CLPFFD-NH2. Here, we studied the effect of changing the residue sequence of the peptide CLPFFD-NH2 on the efficiency of conjugation to AuNP, the stability of the conjugates, and the affinity of the conjugates to the Abeta(More)
A self-biased current reference based on the MOSFET Zero Temperature Coefficient (ZTC) condition is presented. It can be implemented in any CMOS process and it provides a simple alternative to design a reference current suitable for low TC biasing. This topology was designed in a 0.18 μm process to generate 5 μA under a supply voltage from 1.4V to 1.8(More)
A low-voltage high-PSRR CMOS voltage reference operating with picowatt power consumption is presented. The voltage reference is generated from the threshold voltage (V<sub>T</sub>) difference of two transistors biased in weak inversion. The V<sub>T</sub> difference is achieved through its dependence with the transistor dimensions. The high-PSRR is obtained(More)
19 Renal artery stenosis is the main cause of renovascular hypertension and results in 20 ischemic nephropathy characterized by inflammation, oxidative stress, microvascular 21 loss and fibrosis with consequent functional failure. Considering the limited number of 22 strategies that effectively control renovascular hypertension and restore renal function,(More)
Internet of Things (IoT) is a topic of growing interest and intensive research in industry, technological centers and academy, where data communication is one of its most relevant aspects. Since IoT is an open field for new applications, it does not have yet a standard communication protocol. This paper presents the system level design of a WiFi receiver(More)
(1) Superintendency for the Control of Endemic Diseases/SUCEN, São Paulo, SP, Brazil. (2) Faculty of Public Health, USP, São Paulo, SP, Brazil. (3) Parasitology Laboratory, Butantan Institute, São Paulo, SP, Brazil. Correspondence to: Marisa Cristina de Almeida Guimarães, Laboratório de Malacologia da Superintendência de Controle de Endemias (Sucen), Rua(More)