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INTRODUCTION Imbalance in autonomic cardiovascular function increases the risk for sudden death in patients with coronary artery disease (CAD), but the time course of the impact of coronary artery bypass grafting (CABG) on autonomic function has been little studied. Thus, the purpose of the present study was to determine the effects of the CABG on the(More)
OBJECTIVE Impaired parasympathetic modulation increases the risk for sudden death in patients with heart diseases. Therefore, cholinergic stimulation may have a potential protective role. The aim of this study was to verify the effects of pyridostigmine bromide, a reversible cholinesterase inhibitor, on heart rate (HR), blood pressure (BP), HR and BP(More)
We evaluated vascular reactivity after a maximal exercise test in order to determine whether the effect of exercise on the circulation persists even after interruption of the exercise. Eleven healthy sedentary volunteers (six women, age 28 +/- 5 years) were evaluated before and after (10, 60, and 120 min) a maximal exercise test on a treadmill. Forearm(More)
PURPOSE To study the influence of inspiratory flow on the heart rate (HR) responses during the four-second exercise test (4sET) as a method to estimate cardiac vagal activity. METHODS Fifteen healthy subjects performed the 4sET under two experimental situations: a) with maximal individual inspiratory flow (MIF) and b) with a slow inspiratory flow adjusted(More)
This study aimed to evaluate if androgenic-anabolic steroids (AAS) abuse may induce cardiac autonomic dysfunction in recreational trained subjects. Twenty-two men were volunteered for the study. The AAS group (n = 11) utilized AAS at mean dosage of 410 ± 78.6 mg/week. All of them were submitted to submaximal exercise testing using an Astrand-Rhyming(More)
Baroreflex dysfunction, oxidative stress and inflammation, important hallmarks of hypertension, are attenuated by exercise training. In this study, we investigated the relationships and time-course changes of cardiovascular parameters, pro-inflammatory cytokines and pro-oxidant profiles within the hypothalamic paraventricular nucleus of the spontaneously(More)
BACKGROUND The importance of vagal tone on cardiac function and cardiovascular mortality is well established. Although the presence of an enhanced cardiac vagal tone (CVT) is frequently diagnosed using the 12-lead resting electrocardiogram (ECG) in daily practice, most of the proposed criteria have been determined on an empirical basis. Our objective was to(More)
We studied heart rate (HR) responses to vagal electrical stimulation (VES) and the expression of muscarinic acetylcholine receptors (mAChRs) in the rat atria 1 day (SADa) and 20 days (SADc) after sinoaortic denervation (SAD). Arterial blood pressure (BP) was recorded in conscious, unrestrained rats and during vagal electrical stimulation of the vagus nerve.(More)
This study investigated the relationship between oxygen uptake (VO2), cardiac output (Q), stroke volume (SV), and heart rate (HR) in 54 men and 77 women (age = 69 ± 5 years) during incremental effort. Subjects performed a maximal cycle-ergometer test and VO2 was directly measured. HR and SV were assessed by ECG and cardiograph impedance. Regression(More)
PURPOSE Resting cardiac vagal modulation (RCVM) and postexercise vagal reactivation (PEVR) are markers of parasympathetic activity. We investigated whether adaptations in these markers to aerobic training are influenced by baseline autonomic control. METHODS Forty healthy men (19.2 ± 0.8 yr) of similar cardiorespiratory fitness (VO₂peak = 50.4 ± 5.7(More)