Pedro Manuel Vieira Marques

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Healthcare is information driven and knowledge driven. Good healthcare depends on making decisions at the right time and place, using the right patient data and applicable knowledge. Communication is of utmost relevance in today's healthcare settings, in that delivery of care, research, and management all depend on sharing information. The proposed system(More)
Polymerase chain reaction (PCR) was compared with xenodiagnosis performed 20 years after trypanocidal chemotherapy to investigate parasite clearance. Eighty-five seropositive individuals for Chagas disease presenting a positive xenodiagnosis were treated with specific drugs; 37 in the acute phase and 48 in the chronic phase. Fifteen chronic asymptomatic(More)
BACKGROUND The integration of Information Systems (IS) is essential to support shared care and to provide consistent care to individuals--patient-centred care. This paper identifies, appraises and summarises studies examining different approaches to integrate patient data from heterogeneous IS. METHODS The literature was systematically reviewed between(More)
Groove pancreatitis is a rare form of segmental chronic pancreatitis. It involves the anatomic space between the head of the pancreas, the duodenum and the common bile duct. It was first described in the early 1970s, but it remains largely unfamiliar to most physicians. Radiological diagnosis can be challenging, as it is often difficult to differentiate it(More)
Data retrieval and its integration is one of the major problems that face large and complex health organizations. This is especially relevant when patient information is produced in heterogeneous environments. Implementing a Virtual Electronic Patient Record (VEPR) system may provide an adequate and cost-effective solution for most clinical information(More)
A large field study has been performed in the Cochabamba region of Bolivia with the aim of comparing the polymerase chain reaction (PCR) with other diagnostic methods for Chagas' disease. The amplification of Trypanosoma cruzi-specific kinetoplast DNA sequences in blood samples was compared with classical serological methods, specific IgM detection and(More)
A monophasic Salmonella enterica serovar 4,[5],12:i:- phage type DT193 emerged as the dominant serovar in Luxembourg in 2006, when it caused two major outbreaks involving 133 laboratory-confirmed human cases, 24 hospitalisations, and one death. The outbreak strain had an uncommon pulsed-field gel electrophoresis pattern STYMXB.0031 and antibiotic resistance(More)
Although most of pituitary adenomas are benign, they may cause significant burden to patients. Sporadic adenomas represent the vast majority of the cases, where recognized somatic mutations (eg, GNAS or USP8), as well as altered gene-expression profile often affecting cell cycle proteins have been identified. More rarely, germline mutations predisposing to(More)