Pedro Luis Luque-Escamilla

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BACKGROUND Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defining CpG islands (CGIs), since all current approaches rely on a large parameter space formed by the thresholds of length, CpG fraction and G+C content. RESULTS Given the higher(More)
BACKGROUND Unmethylated stretches of CpG dinucleotides (CpG islands) are an outstanding property of mammal genomes. Conventionally, these regions are detected by sliding window approaches using %G + C, CpG observed/expected ratio and length thresholds as main parameters. Recently, clustering methods directly detect clusters of CpG dinucleotides as a(More)
In this paper, a median based filter called relaxed median filter is proposed. The filter is obtained by relaxing the order statistic for pixel substitution. Noise attenuation properties as well as edge and line preservation are analyzed statistically. The trade-off between noise elimination and detail preservation is widely analyzed. It is shown that(More)
A new measure of quality is proposed for evaluating the performance of available methods of image segmentation and edge detection. The technique is intended for the evaluation of low error results and features an objective assessment of discrepancy with respect to the theoretical edge, in tandem with subjective visual evaluation using both the neighbourhood(More)
To remove impulsive noise, several variants of median-type filters are presented. They use some prior information provided by the probabilistic composition model of the class of the image being processed. This information is doubly applied; first, in elaborating a noise-estimation mask for the preselection of the pixels which must be filtered; and second,(More)
Using the Jensen-Shannon divergence of grey level his-tograms obtained by sliding a double window over an image , an edge-detector is presented. A new technique for linking unconnected edge points, based on estimated directions , is also described. The method is suitable for tex-tured images and has proved to be fairly robust in the presence of impulsive(More)
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