Pedro Afonso

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PURPOSE To determine the rate at which computed tomographically guided pelvic percutaneous bone biopsy in men with metastatic castration-resistant prostate cancer (mCRPC) yields adequate tissue for genomic profiling and to identify issues likely to affect diagnostic yields. MATERIALS AND METHODS This study was institutional review board approved, and(More)
Sleep disturbances are widespread in schizophrenia, and one important concern is to determine the impact of this disruption on self-reported sleep quality and quality of life (QoL). Our aim was to evaluate the sleep-wake cycle in a sample of patients with schizophrenia (SZ), and whether sleep patterns differ between patients with predominantly negative(More)
Soft tissue sarcomas are rare, but early, accurate diagnosis with subsequent appropriate treatment is crucial for the clinical outcome. The ESSR guidelines are intended to help radiologists in their decision-making and support discussion among clinicians who deal with patients with suspected or proven soft tissue tumors. Potentially malignant lesions(More)
OBJECTIVE The aim of this study was to compare the endogenous melatonin sleep-promoting effect in schizophrenic patients to a sample of healthy controls. METHODS Thirty-four schizophrenia outpatients (SP) and 34 healthy subjects (HS) participated in this study. Wrist-actigraphy recordings and a sleep diary were used for sleep-wake cycle assessment. The(More)
OBJECTIVES The aim of this study was to examine the differences between a sample of patients with schizophrenia and a sample of healthy controls in terms of sleep patterns and self-reported sleep quality and quality of life (QoL). METHODS Thirty-four schizophrenia outpatients (SP), 12 women and 22 men and 34 healthy subjects (HS), 15 women and 19 men,(More)
Lifelong learning (LLL) is an essential feature for the doctor to keep clinically updated and has been described as an indicator of competence and professionalism. The aim of this study was to evaluate the association between career satisfaction in psychiatry, lifelong learning, and commitment in scientific activities, taking into account other personal and(More)
MPS.BR describes a software processes gradual improvement without specifying how to implement it. In this context, this paper presents a free software tools suite to support the MPS.BR implementation: SPIDER-Tool Suite for Quality. The project team has collaboration of SOFTEX certified professionals. O projeto SPIDER ( tem, como um dos(More)
OBJECTIVE Patients with schizophrenia (SZ) often present sleep complaints, and patients with sleep disturbances are at a greater risk for symptom worsening after antipsychotic discontinuation. Long-term adherence to antipsychotic treatment remains a challenge for clinicians, and the relationship between quality of sleep and treatment adherence in SZ(More)
The spine is the most common site of osseous involvement by tuberculosis. Diagnosis of tuberculous spondylodiskitis, also known as Pott's disease, is often difficult due to its insidious onset and nonspecific clinical presentation. Along with a high level of suspicion, familiarity with its imaging characteristics is the basis for establishing the correct(More)