Pedram Sendi

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BACKGROUND Evidence on the effectiveness of highly active antiretroviral therapy (HAART) for HIV-infected individuals is limited. Most clinical trials examined surrogate endpoints over short periods of follow-up and there has been no placebo-controlled randomised trial of HAART. Estimation of treatment effects in observational studies is problematic,(More)
PRINCIPLES Citation metrics are commonly used as a proxy for scientific merit and relevance. Papers published in English, however, may exhibit a higher citation frequency than research articles published in other languages, though this issue has not yet been investigated from a Swiss perspective where English is not the native language. METHODS To assess(More)
BACKGROUND Genotypic antiretroviral resistance testing (GRT) in HIV infection with drug resistant virus is recommended to optimize antiretroviral therapy, in particular in patients with virological failure. We estimated the clinical effect, cost and cost-effectiveness of using GRT as compared to expert opinion in patients with antiretroviral treatment(More)
BACKGROUND Several strategies to optimise the use of antibiotics have been developed. Most of these interventions can be classified as educational or restrictive. Restrictive measures are considered to be more effective, but the enforcement of these measures may be difficult and lead to conflicts with prescribers. Any intervention should be aimed at targets(More)
Cost-effectiveness analysis (CEA) has been adopted as method for informing health care decision-makers about alternative uses of health care resources. By comparing the incremental costs and effects of a new intervention relative to the existing approach to dealing with the same patients, decision-makers seek to choose those investments that lead to the(More)
INTRODUCTION The mental foramen (MF) is an important landmark in dentistry. Knowledge of its position is central to perform block anesthesia of the mental nerve or to avoid nerve damage during surgical procedures in the premolar area of the mandible. The present radiographic study aimed at evaluating the location and dimension of the MF and measuring(More)
It has been argued that asylum seekers (AS) consume more health care resources than the local Swiss population. In this study we compare the health care costs of a group of AS who attended an outpatient clinic (OPC) at the University Hospital in Basel, Switzerland, between 2000 and 2003 with a control group of local patients attending the same OPC. Using(More)
OBJECTIVE To investigate the effects of tooth loss on gait stability in a healthy elderly population. METHODS A case-control study was conducted among healthy and prosthetically well-restored seniors over the age of 65 years. The test group comprised 24 edentulous participants who were restored with complete dentures in the upper jaw and an overdenture(More)
Objective: Osteoporosis is a major public health concern in Switzerland and is associated with an increased rate of bone factures, health care costs, mortality and loss of quality of life. Risedronate has been shown to effectively prevent fractures in patients with osteoporosis. We examined the cost-effectiveness of risedronate from the Swiss health care(More)
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