Payal Hasmukhlal Patil

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The aim of present work was the formulation of Bi-layer tablets of Piracetam and Vinpocetine, so that synergistic effect of this combination could be used for the effective treatment of Alzheimer Disease. Wet granulation process was used for the formulation of both layers and the final film coated tablets were evaluated for the thickness, weight variation,(More)
The objective of the present work was to enhance the solubility and dissolution rate of the drug raloxifene HCl (RLX), which is poorly soluble in water. The solubility of RLX was observed to increase with increasing concentration of hydroxypropyl methylcellulose (HPMC E5 LV). The optimized ratio for preparing a solid dispersion (SD) of RLX with HPMC E5 LV(More)
The objective of the present work was to enhance the solubility and dissolution of practically water-insoluble drug raloxifene HCl (RLX), for the same two approaches that were used. In the first approach, drug was kneaded with hydroxypropyl-β-cyclodextrin (HPβCD), and in the second one drug was cogrinded with modified guar gum (MGG). The drug-cyclodextrin(More)
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