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The introduction of typical antipsychotics over six decades ago signaled an important milestone in psychiatry. However, second-generation antipsychotics ameliorated the positive symptoms of schizophrenia but displayed limited effectiveness for the negative and cognitive symptoms. In addition, while the newer antipsychotics produced fewer motor side effects,(More)
Metal-organic frameworks can offer pore geometries that are not available in zeolites or other porous media, facilitating distinct types of shape-based molecular separations. Here, we report Fe2(BDP)3 (BDP(2-) = 1,4-benzenedipyrazolate), a highly stable framework with triangular channels that effect the separation of hexane isomers according to the degree(More)
Magnetism in the orthorhombic metal CaFe(4)As(3) was examined through neutron diffraction for powder and single crystalline samples. Incommensurate [q(m) ≈ (0.37-0.39) × b*] and predominantly longitudinally (|| b) modulated order develops through a 2nd order phase transition at TN = 89.63(6) K with a 3D Heisenberg-like critical exponent β = 0.365(6). A 1st(More)
Active G protein-coupled receptor (GPCR) conformations not only are promoted by agonists but also occur in their absence, leading to constitutive activity. Association of GPCRs with intracellular protein partners might be one of the mechanisms underlying GPCR constitutive activity. Here, we show that serotonin 5 hydroxytryptamine 6 (5-HT6) receptor(More)
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