Paweł D Zaremba

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Antiepileptic drugs (AEDs) affect various neurotransmitters (i.e. GABA, glutamate), receptors (i.e. GABAergic, glutamatergic), and ion channels (i.e. for sodium or calcium) which is responsible for their anticonvulsant activity. However, this broad spectrum of action may be also utilized in other pathological conditions. For example, both conventional and(More)
Testosterone -- the gonadal sex steroid hormone plays an important role in the central nervous system (CNS) development. One of the less known testosterone actions is neuroprotection. There are some evidences supporting the hypothesis that testosterone may act protectively in neurodegenerative disorders, e.g. Alzheimer's disease (AD), mild cognitive(More)
liver, a 5.6-fold change in Naþ Kþ ATPase capacity ‘drives’ a 1.63-fold change in V̇O2 , while in vertebrate brain, a 3.78-fold change in Naþ Kþ ATPase ‘drives’ a 1.63-fold change in V̇O2 ; thus the ratios of change in metabolic flux capacities/change in Na þ Kþ ATPase capacities, the c i values, are 0.29 (for liver) and 0.43 (for brain). We do not have(More)
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