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Abnormal phosphorylation of tau protein represents one of the major candidate pathological mechanisms leading to Alzheimer's disease (AD) and related tauopathies. Altered phosphorylation status of neuronal tau protein may result from upregulation of tau-specific kinases or from inhibition of tau-specific phosphatases. Increased expression of the protein(More)
In this study the pulsation-pressure relationship in an experimental model of aneurysms was analyzed. In addition, we have examined pulsatility of the aneurysmal wall reinforced by Guglielmi Detachable Coils (GDC). Bifurcation (BAn), aneurysms (LAn) and bilobar (BiA) aneurysms were produced in 15 mongrel dogs. The aneurysmal dome was constructed from a(More)
This paper presents the FE formulation for which the only incompatibility is in the inter-element tractions. The boundary tractions and displacements are defined using the Betti's reciprocity, similarly as that used by BEM. As the integration for the stiffness matrix formulation is taken over the element boundaries only, the shape of matrix can be more(More)
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