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Generation of ligand-receptor alliances by "SEA" module-mediated cleavage of membrane-associated mucin proteins.

• Daniel H. Wreschner, Michael A McGuckin, +11 authors Siamon Gordon
• Protein science : a publication of the Protein…
• 2002

A mechanism is described whereby one and the same gene can encode both a receptor protein as well as its specific ligand. Generation of this receptor-ligand partnership is effected by proteolytic… (More)

Proportioning of Steel Fibre Reinforced Concrete Mixes for Pavement Construction and Their Impact on Environment and Cost

• Constantia Achilleos, Diofantos G. Hadjimitsis, Kyriacos Neocleous, Kypros Pilakoutas, Pavlos O. Neophytou, Stelios Kallis
• 2011

Steel fibre reinforced concrete (SFRC) is a construction material investigated for more than 40 years including for pavement applications. A number of studies have demonstrated the technical merits… (More)

Surfactant protein D augments bacterial association but attenuates major histocompatibility complex class II presentation of bacterial antigens.

• Soren Tranberg Hansen, Bernice Lo, Kathy Evans, Pavlos O. Neophytou, Uffe Holmskov, Jo Rae Wright
• American journal of respiratory cell and…
• 2007

Surfactant protein D (SP-D) is a secreted pattern recognition molecule associated with lung surfactant and mediates the clearance of pathogens in multiple ways. SP-D is an established part of the… (More)

Mutational analysis of hMsh6 in Israeli HNPCC and HNPCC-like Families

• Shiri Dovrat, Arié Figer, +7 authors Eitan Friedman
• Familial Cancer
• 2005

Germline mutations in DNA mismatch repair (DNA-MMR) genes, mainly hMlh1 and hMsh2, underlie Hereditary Non-Polyposis Colorectal Cancer (HNPCC). Germline hMSH6 gene mutations have been reported in a… (More)

Detection of a novel nonsense mutation and an intragenic polymorphism in the PKD1 gene of a Cypriot family with autosomal dominant polycystic kidney disease

• Pavlos O. Neophytou, Rolandos Constantinides, Akis Lazarou, Alkis M Pierides, C. Constantinou Deltas
• Human Genetics
• 1996

Mutations in the PKD1 gene on the short arm of chromosome 16 account for 85%–90% of polycystic kidney disease patients in the Caucasian population. After the recent characterization of the gene, we… (More)

New amino acid polymorphism, Ala/Val4058, in exon 45 of the polycystic kidney disease 1 gene: evolution of alleles

• Rolandos Constantinides, Stavroulla L Xenophontos, Pavlos O. Neophytou, Shinsuke Nomura, Alkis M Pierides, C. Constantinou Deltas
• Human Genetics
• 1997

The PKD1 gene, which is responsible for the most common form of autosomal dominant polycystic kidney disease, has recently been cloned and sequenced. Many disease-causing mutations have been… (More)

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