Pavel Sturm

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104 cAMP analogs, most of them modified in the adenine moiety, were tested as activators of cAMP-dependent protein kinase I (from rabbit or rat skeletal muscle) and kinase II (from bovine heart or rat skeletal muscle). When tested singly, only 2-phenyl-1,N6-etheno-cAMP showed a considerably (sevenfold) higher potency as an activator of kinase II than of(More)
3-Aminopyrrolidines bearing acyl substituents on either nitrogen and N-acylated 1,4-diazabicyclo[3.2.1]octanes are potent microfilaricides in the Litomosoides carinii gerbil test system but have no effect on adult worms. The high activity of the pyrrolidine derivatives establishes that diethylcarbamazine (DEC) like antifilarial activity does not require(More)
Despite the copious advances in acoustic techniques and devices for measuring and displaying acoustic parameters, a steady component of a phonetician’s scientific method remains to be – to this very day – our hearing. This paper therefore focuses on a historical device shared between acoustics and auditory phonetic analysis: Rudolph Koenig’s Grand(More)