Pavel Piterkin

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We investigated whether object familiarization was related to novel-object preference in the novel-object preference (NOP) test in rats. In Experiment 1, we found that no significant correlation existed between the time spent investigating 2 identical copies of a sample object and the degree of preference for a novel object. In Experiment 2, rats(More)
Damage to the perirhinal cortex (PRh) in rats impairs anterograde object-recognition memory after retention intervals of up to several hours, but there is little direct evidence to link PRh function to object-recognition abilities after substantially longer intervals that span several days or weeks. We assessed the effects of PRh lesions on anterograde(More)
Recent evidence suggests that rats require an intact hippocampus in order to recognize familiar objects when they encounter them again in a different context. The two experiments reported here further examined how changes in context affect rats' performance on the novel-object preference (NOP) test of object-recognition memory, and how those effects(More)
Memory Impairment Following Transient Global Cerebral Ischemia in Rats: Relationship to Neuropathology in the Hippocampus and Perirhinal Cortex Pavel Piterkin Memory impairments following global cerebral ischemia have traditionally been associated with damage to the hippocampus (HPC), but some ensuing impairments, such as object-recognition deficits,(More)
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