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  • Pavel Ostasov, Jan Sýkora, Jana Brejchová, Agnieszka Olżyńska, Martin Hof, Petr Svoboda
  • Chemistry, Medicine
  • Chemistry and physics of lipids
  • 2013 (First Publication: 1 February 2013)
  • HEK293 cells stably expressing δ-opioid receptor were labeled first with fluorescent analog of cholesterol, 22-NBD-cholesterol, exposed to cholesterol-depleting agent β-cyclodextrin (β-CDX) andExpand
  • Jana Brejchová, Jan Sýkora, +5 authors Petr Svoboda
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 2011 (First Publication: 1 December 2011)
  • Biophysical studies of fluorescence anisotropy of DPH and Laurdan generalized polarization were performed in plasma membranes (PM) isolated from control and cholesterol-depleted HEK293 cells stablyExpand
  • Pavel Ostasov, Lenka Bouřová, Lucie Hejnova, Jiri Novotný, Petr Svoboda
  • Biology, Medicine
  • Journal of receptor and signal transduction…
  • 2007 (First Publication: 1 January 2007)
  • We monitored the radioligand-binding characteristics of thyrotropin-releasing hormone (TRH) receptors, functional activity of Gq/11α proteins, and functional status of the whole signaling cascade inExpand
  • Jana Brejchová, Jan Sýkora, +5 authors Petr Svoboda
  • Chemistry, Medicine
  • Biochimica et biophysica acta
  • 2015 (First Publication: 1 March 2015)
  • UNLABELLED Here we investigated the effect of disruption of plasma membrane integrity by cholesterol depletion on thyrotropin-releasing hormone receptor (TRH-R) surface mobility in HEK293 cellsExpand
  • Pavel Ostasov, Jan Krůšek, Dana Durchánková, Petr Svoboda, Jiri Novotný
  • Biology
  • 2008 (First Publication: 1 March 2008)
  • The molecular mechanisms involved in GPCR-initiated signaling cascades where the two receptors share the same signaling cascade, such as thyrotropin-releasing hormone (TRH) and angiotensin II (ANGExpand
  • Pavel Ostasov, Jan Krůšek, Dana Durchánková, Petr Svoboda, Jiri Novotný
  • Medicine
  • Cell biochemistry and function
  • 2008
  • The molecular mechanisms involved in GPCR-initiated signaling cascades where the two receptors share the same signaling cascade, such as thyrotropin-releasing hormone (TRH) and angiotensin II (ANGExpand
  • Zuzana Burdíková, Martin Capek, +4 authors Lucie Kubínová
  • Medicine, Materials Science
  • Microscopy and microanalysis : the official…
  • 2010 (First Publication: 1 December 2010)
  • Testate amoebae (TA) are a group of free-living protozoa, important in ecology and paleoecology. Testate amoebae taxonomy is mainly based on the morphological features of the shell, as examined byExpand