Pavel K Kuzmichev

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P75NTR is a type I integral membrane protein that plays a key role in neurotrophin signaling. However, structural data for the receptor in various functional states are sparse and controversial. In this work, we studied the spatial structure and mobility of the transmembrane and intracellular parts of p75NTR, incorporated into lipid-protein nanodiscs of(More)
Growth hormone somatotropin and its membrane receptor GHR (growth hormone receptor) belonging to a superfamily of the type I receptors with tyrosine kinase activity are involved in the intercellular signal transduction cascade that regulates a number of important physiological and pathological processes in humans. Binding with somatotropin triggers a(More)
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