Learn More
  • P A Gusev
  • 1994
Comparative analysis of the probability, direction and magnitude of changes of the mean firing rates for the background and L-glutamate--(Glu) and acetylcholine--(ACh) induced activity of single sensorimotor cortical neurons of unanesthetized rats showed that more significant changes occurred in reaction to the applications of Glu. Increases of Glu-induced(More)
a r t i c l e i n f o a b s t r a c t We discuss the problem of counting vertices in Gelfand–Zetlin polytopes. Namely, we deduce a partial differential equation with constant coefficients on the exponential generating function for these numbers. For some particular classes of Gelfand–Zetlin poly-topes, the number of vertices can be given by explicit(More)
A morphometric investigation of various components of the synapses of neurons of the sensorimotor region of the cerebral cortex of rats with different variants of combined and uncombined repeated microiontophoretic application of glutamate and acetylcholine has been carried out, A substantial dependence of the character and expressivity of the(More)
Numerous studies have demonstrated an important role for cholinergic and glutamatergic signal transduction in the cerebral cortex in the processes of learning and memory. The results of our own studies have shown [1] that repeated combined microapplication of glutamate and acetylcholine induce ultrastructural changes in axodendritic synapses, with increases(More)
As a result of acetylcholine iontophoresis with different currents 3-fold increase of transmitter compared with the threshold one for reaction has been shown not to result in change of a type of reaction pattern more than in 80.3% of neurones. Such increase of action force is quite enough for the significant lengthening of the reaction excitatory components(More)
The last decade has seen considerable success in studies of glutamate and its receptors in the mechanisms of brain plasticity. NMDA g'.utamate receptors are particularly important for induction of plastic rearrangements [3]. Data have been obtained which demonstrate that this type of receptor is associated with induction of long-term potentiation in the(More)
The effect of muscarinic antagonist atropine on thickness of postsynaptic density of axodendritic synapses was studied in the sensorimotor region of the brain cortex of rats during paired repeated microapplication of glutamate and acetylcholine. In the applied conditioning paradigm atropine significantly decreased morphological dimensions of the(More)
Assessment of total vitamin D intake from foods and dietary supplements (DSs) may be incomplete if 25-hydroxyvitamin D [25(OH)D] intake is not included. However, 25(OH)D data for such intake assessments are lacking, no food or DS reference materials (RMs) are available, and comparison of laboratory performance has been needed. The primary goal of this study(More)
An essential role in the processes of the perception and recording of diverse external signals by the brain belongs to the various neuromediator systems participating in this. At the same time, the mechanisms involved in the interaction of such signals at the level of individual neurons and of small neuronal groups remain unclear. The data of our preceding(More)