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Pyruvate incubation enhances glycogen stores and sustains neuronal function during subsequent glucose deprivation
The use of energy substrates, such as lactate and pyruvate, has been shown to improve synaptic function when administered during glucose deprivation. In the present study, we investigated whetherExpand
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Cellular Links between Neuronal Activity and Energy Homeostasis
Neuronal activity, astrocytic responses to this activity, and energy homeostasis are linked together during baseline, conscious conditions, and short-term rapid activation (as occurs with sensory orExpand
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Nicotinamide pre-treatment ameliorates NAD(H) hyperoxidation and improves neuronal function after severe hypoxia
Prolonged hypoxia leads to irreversible loss of neuronal function and metabolic impairment of nicotinamide adenine dinucleotide recycling (between NAD(+) and NADH) immediately after reoxygenation,Expand
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Age-related metabolic fatigue during low glucose conditions in rat hippocampus
Previous reports have indicated that with aging, intrinsic brain tissue changes in cellular bioenergetics may hamper the brain's ability to cope with metabolic stress. Therefore, we analyzed theExpand
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Age-Induced Alterations in Hippocampal Function and Metabolism.
As the nervous system ages, a variety of changes occur in metabolism supporting glial and neuronal function, resulting in greater susceptibility to disease conditions. Changes with aging in theExpand
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Low-Cost Dynamometers - A Grip Measurement and Logging Solution
The aim of the project is to develop a grip measurement and data logging product which can be used as an exercise ball for patients who have undergone orthopedic surgery and as a recoveryExpand